Eisner Brian H, Pedro Renato, Namasivayam Saravanan, Kambadakone Avinash, Sahani Dushyant V, Dretler Stephen P, Monga Manoj
Department of Urology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA.
Urology. 2008 Sep;72(3):517-20. doi: 10.1016/j.urology.2008.03.034. Epub 2008 May 27.
To examine the differences in ureteral dilation and calculus size between obstructing proximal and distal ureteral stones.
A retrospective review of computed tomography (CT) scans from 176 consecutive patients with obstructing ureteral calculi was performed. For the calculi, the axial diameter was defined as the largest stone diameter on the axial CT images, and the coronal length was defined as the cephalocaudal length of the stone measured on the coronal CT images. Univariate and multivariate statistical analyses were performed.
A total of 65 proximal and 111 distal ureteral calculi were analyzed. On univariate analysis, the proximal calculi were associated with a greater degree of ureteral dilation (mean 6.1 mm vs 5.3 mm, P = .01) and had a greater coronal length (mean 9.9 mm vs 8.3 mm, P = .005) than distal calculi. This association was also true on the multivariate analysis, which controlled for age and sex (P = .0004). No statistically significant difference was found in the axial calculus diameter for the proximal and distal stones (mean 5.3 mm vs 5.0 mm, P = .29). In a subset of 50 patients whose contralateral ureters (without stones) were measured for control comparison, the ureteral dilation in the ureters with stones was significantly greater than in the control ureters (proximal ureter 6.2 mm vs 4.3 mm, P = .001; distal ureter 4.7 mm vs 3.8 mm, P = .004). For proximal calculi, 72.3% were associated with ureteral dilation of less than 7 mm, 23.1% with 7-10 mm, and 4.6% with greater than 10 mm. For the distal calculi, 90.1% were associated with ureteral dilation of less than 7 mm, 6.3% with 7-10 mm, and 3.6% with greater than 10 mm. The coronal length was the largest measured diameter in 94% of the calculi, and the mean calculus coronal length was significantly greater than the mean axial diameter (8.9 mm vs 5.1 mm, respectively, P < .001).
The results of our study have shown that proximal ureteral calculi are associated with a significantly greater degree of ureteral dilation and larger coronal length than are distal calculi. These findings should guide the endoscopist in planning intracorporeal ureteroscopic lithotripsy. We suggest obtaining CT coronal images to more accurately characterize obstructing ureteral stones.
探讨输尿管近端和远端梗阻性结石在输尿管扩张及结石大小方面的差异。
对176例连续性输尿管梗阻性结石患者的计算机断层扫描(CT)图像进行回顾性分析。对于结石,轴径定义为轴向CT图像上结石的最大直径,冠状长度定义为在冠状CT图像上测量的结石头端至尾端的长度。进行单因素和多因素统计分析。
共分析了65枚输尿管近端结石和111枚输尿管远端结石。单因素分析显示,近端结石较远端结石伴有更严重的输尿管扩张(平均6.1 mm对5.3 mm,P = 0.01),且冠状长度更长(平均9.9 mm对8.3 mm,P = 0.005)。在控制年龄和性别的多因素分析中,这种关联同样成立(P = 0.0004)。近端和远端结石的轴径差异无统计学意义(平均5.3 mm对5.0 mm,P = 0.29)。在50例对侧输尿管(无结石)进行测量以作对照比较的患者亚组中,有结石侧输尿管的扩张明显大于对照侧输尿管(近端输尿管6.2 mm对4.3 mm,P = 0.001;远端输尿管4.7 mm对3.8 mm,P = 0.004)。对于近端结石,72.3%伴有小于7 mm的输尿管扩张,23.1%伴有7 - 10 mm的扩张,4.6%伴有大于10 mm的扩张。对于远端结石,90.1%伴有小于7 mm的输尿管扩张,6.3%伴有7 - 10 mm 的扩张,3.6%伴有大于10mm的扩张。94%的结石冠状长度为最大测量直径,结石平均冠状长度显著大于平均轴径(分别为8.9 mm对5.1 mm,P < 0.001)。
我们的研究结果表明,输尿管近端结石较远端结石伴有更显著的输尿管扩张及更长的冠状长度。这些发现应指导内镜医师规划体内输尿管镜碎石术。我们建议获取CT冠状图像以更准确地描述梗阻性输尿管结石。