Hansen P B, Rasmussen J V, Bak M
Odense Universitetshospital, kirurgisk afdeling A.
Ugeskr Laeger. 1998 Apr 13;160(16):2401-2.
The breast is an uncommon site for metastasis from extramammary primaries. A 43-year-old woman presented with a lump in the left breast. A tumour with atypical microcalcifications was seen on the mammogram. Needle aspiration cytology revealed adenocarcinoma cells. The final histological diagnosis was papillary adenocarcinoma with psammoma bodies, probably secondary to an ovarian carcinoma. A bilateral carcinoma of the ovaries was subsequently diagnosed and treated. A mammary tumour with an atypical growth pattern and the absence of in situ carcinoma should always prompt the pathologist to considering the possibility of a metastatic tumour even though this is a rare occurrence. Earlier recognition of metastatic tumours to the breast may result in initiation of appropriate therapy and will preclude unnecessary surgical procedures.
乳腺是乳腺外原发性肿瘤转移的罕见部位。一名43岁女性因左乳肿块就诊。乳房X线照片上可见一个伴有非典型微钙化的肿瘤。针吸细胞学检查发现腺癌细胞。最终组织学诊断为伴有砂粒体的乳头状腺癌,可能继发于卵巢癌。随后诊断并治疗了双侧卵巢癌。即使这种情况很少见,但具有非典型生长模式且无原位癌的乳腺肿瘤应始终促使病理学家考虑转移性肿瘤的可能性。早期识别乳腺转移性肿瘤可能会促使开始适当的治疗,并避免不必要的外科手术。