Arruda Tarciana Albuquerque Marenga de, Amorim Melania Maria Ramos de, Souza Alex Sandro Rolland
Centro de Atenção à Mulher - Instituto Materno Infantil Professor Fernando Figueira (IMIP), Recife, PE.
Rev Assoc Med Bras (1992). 2008 Mar-Apr;54(2):122-6. doi: 10.1590/s0104-42302008000200013.
To establish magnitude and temporal trend of deaths by congenital malformations in Pernambuco state in Northeast of Brazil, from 1993 to 2003.
This is an observational descriptive study, with the temporal trend including all cases of death caused by congenital malformations, obtained from the database of the Mortality Information System of the Ministry for Health.
From 1993 to 2003, 3.960 infant deaths and 989 stillbirths caused by congenital malformations were registered in Pernambuco. The coefficients of fetal, early neonatal, perinatal, neonatal and infant (< 1 year) mortality were 0.57, 1.20, 1.76, 1.59 and 2.33, respectively. A rising tendency was observed in the temporal curve from 1993 to 2003 when coefficients of early neonatal (p = 0.003), perinatal (p = 0.005), neonatal (p = 0.0007) and infant (p = 0.02) mortality were studied but no statistical significance was detected for the fetal mortality coefficient (p= 0.55).
From 1993 to 2003 a rising tendency in the coefficients of early neonatal, perinatal, neonatal and infant mortality was found in the state of Pernambuco. This trend may have been be influenced by an improvement in the death registration records and by a decline of infant mortality in the state of Pernambuco.
确定1993年至2003年巴西东北部伯南布哥州先天性畸形所致死亡的规模和时间趋势。
这是一项观察性描述性研究，时间趋势研究纳入了所有先天性畸形所致死亡病例，数据来源于卫生部死亡率信息系统数据库。
1993年至2003年，伯南布哥州登记了3960例先天性畸形所致婴儿死亡和989例死产。胎儿、早期新生儿、围产期、新生儿和婴儿（<1岁）死亡率系数分别为0.57、1.20、1.76、1.59和2.33。研究1993年至2003年的时间曲线时，观察到早期新生儿（p = 0.003）、围产期（p = 0.005）、新生儿（p = 0.0007）和婴儿（p = 0.02）死亡率系数呈上升趋势，但胎儿死亡率系数未检测到统计学意义（p = 0.55）。
1993年至2003年，伯南布哥州早期新生儿、围产期、新生儿和婴儿死亡率系数呈上升趋势。这一趋势可能受到死亡登记记录改善以及伯南布哥州婴儿死亡率下降的影响。
