Yiş Uluç, Kurul Semra Hiz, Cakmakçi Handan, Dirik Eray
Department of Pediatrics, Division of Child Neurology, Dokuz Eylül University School of Medicine, 35340, Izmir, Turkey.
Eur J Pediatr. 2008 Sep;167(9):973-8. doi: 10.1007/s00431-008-0714-1. Epub 2008 May 28.
Mycoplasma pneumoniae is an important pathogen which causes nervous system disorders during or after the course of a respiratory tract infection. The exact pathogenic mechanism which causes neurological disorders still remains unknown. Although meningoencephalitis and acute disseminated encephalomyelitis are common complications, there are few cases of acute transverse myelitis and isolated abducens nerve palsy associated with M. pneumoniae infection in childhood. The association between ocular myasthenia gravis and M. pneumoniae infection has not been described before. Here, we describe five patients with different nervous system complications associated with M. pneumoniae infection and discuss the pathological features of central nervous system involvement.
肺炎支原体是一种重要的病原体，可在呼吸道感染期间或之后引发神经系统疾病。导致神经疾病的确切致病机制仍不清楚。虽然脑膜脑炎和急性播散性脑脊髓炎是常见并发症，但儿童期与肺炎支原体感染相关的急性横贯性脊髓炎和孤立性展神经麻痹病例较少。此前尚未描述过重症肌无力与肺炎支原体感染之间的关联。在此，我们描述了5例与肺炎支原体感染相关的不同神经系统并发症患者，并讨论了中枢神经系统受累的病理特征。
