Ou Yang Owen, Loi Ken, Liew Victor, Talbot Michael, Jorgensen John
Upper GI, Advanced Laparoscopic and Bariatric Surgery, St George Private Hospital, Sydney, Australia.
Obes Surg. 2008 Dec;18(12):1575-80. doi: 10.1007/s11695-008-9554-3. Epub 2008 May 28.
In our centre laparoscopic Roux-en-Y gastric bypass (LRYGBP) is the most effective weight loss surgical procedure performed. However, LRYGBP may be associated with higher risk of peri- and postoperative complications in contrast to a purely restrictive procedure to justify this procedure on all comers. Laparoscopic sleeve gastrectomy (LSG) as a staged procedure may be an alternate risk reduction strategy. The aim of this study is to report on the short-term outcomes of LSG, the effect on operative risk reduction and resolution of comorbidities.
A prospective review of 138 patients who underwent consecutive LSG from November 2004 to November 2006 was performed. Data were collected on all patients who attended the three to six monthly clinical follow-up and/or the patient questionnaire. Data collection included demographics, degree of weight reduction, postoperative complications, and changes in comorbidities.
Median BMI was 50.60 kg/m(2) (33-82). Of the patients, 46.38% had a BMI >or=50 kg/m(2). The overall median postoperative excess weight loss (EWL) was 43.26%, 31.08% at 6 months, 54.50% at 12 months, 51.47% at 18 months and 46.05% at 24 months. Of the patients, 39% had resolution of type 2 diabetes mellitus, 48% had resolution of dyslipidemia, 29% in hypertension, 52% in obstructive sleep apnea. Complication rate was 5.07% and four patients needed further surgical intervention. The mortality rate was zero.
LSG does minimize postoperative complication rates significantly on high-risk patients and achieves effective short-term weight loss with resolutions in comorbidities. Additional studies are required to evaluate LSG as a stand-lone procedure.
在我们中心,腹腔镜Roux-en-Y胃旁路术(LRYGBP)是实施的最有效的减肥手术。然而,与单纯的限制性手术相比,LRYGBP可能与围手术期及术后并发症的较高风险相关,这使得该手术无法适用于所有患者。腹腔镜袖状胃切除术(LSG)作为一种分期手术可能是一种降低风险的替代策略。本研究的目的是报告LSG的短期结果、对降低手术风险的影响以及合并症的解决情况。
对2004年11月至2006年11月连续接受LSG的138例患者进行前瞻性回顾。收集了所有参加每三到六个月临床随访和/或患者问卷调查的患者的数据。数据收集包括人口统计学、体重减轻程度、术后并发症以及合并症的变化。
中位体重指数(BMI)为50.60kg/m²(33 - 82)。其中46.38%的患者BMI≥50kg/m²。术后总体中位超重减轻(EWL)为43.26%,6个月时为31.08%,12个月时为54.50%,18个月时为51.47%,24个月时为46.05%。其中,39%的患者2型糖尿病得到缓解,48%的患者血脂异常得到缓解,29%的患者高血压得到缓解,52%的患者阻塞性睡眠呼吸暂停得到缓解。并发症发生率为5.07%,4例患者需要进一步手术干预。死亡率为零。
LSG确实能显著降低高危患者的术后并发症发生率,并实现有效的短期体重减轻以及合并症的缓解。需要进一步的研究来评估LSG作为一种独立手术的效果。