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引起马驹腹泻的微小隐孢子虫的遗传多样性和人畜共患病潜力。

Genetic diversity and zoonotic potential of Cryptosporidium parvum causing foal diarrhea.

作者信息

Grinberg A, Learmonth J, Kwan E, Pomroy W, Lopez Villalobos N, Gibson I, Widmer G

机构信息

Massey University, Institute of Veterinary, Animal and Biomedical Sciences, Infectious Disease and Public Health Group, Private Bag 11222, Palmerston North, New Zealand.

出版信息

J Clin Microbiol. 2008 Jul;46(7):2396-8. doi: 10.1128/JCM.00936-08. Epub 2008 May 28.

Abstract

Cryptosporidium isolates from diarrheic foals in New Zealand (n = 9) were identified as C. parvum, subtyped at two polymorphic loci, and compared with human (n = 45) and bovine (n = 8) isolates. Foal C. parvum isolates were genetically diverse, markedly similar to human and bovine isolates, and carried GP60 IIaA18G3R1 alleles, indicating a zoonotic potential.

摘要

从新西兰腹泻马驹中分离出的隐孢子虫(n = 9)被鉴定为微小隐孢子虫,在两个多态性位点进行了亚型分析,并与人类(n = 45)和牛(n = 8)的分离株进行了比较。马驹微小隐孢子虫分离株在基因上具有多样性,与人类和牛的分离株明显相似,并携带GP60 IIaA18G3R1等位基因,表明具有人畜共患病潜力。

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