针对HIV阴性经典型卡波西肉瘤中的雷帕霉素靶蛋白（mTOR）
Targeting mTOR in HIV-Negative Classic Kaposi's Sarcoma.
作者信息
Merimsky Ofer, Jiveliouk Irina, Sagi-Eisenberg Ronit
机构信息
Unit of Bone and Soft Tissue Oncology, Division of Oncology, Tel-Aviv Sourasky Medical Center, 6 Weitzman Street, Tel-Aviv 64239, Israel.
出版信息
Sarcoma. 2008;2008:825093. doi: 10.1155/2008/825093.
Abstract
A 66-year old female with HIV-negative classic Kaposi's sarcoma responded to mTOR targeting by rapamycin. The response was well documented by PET-CT. This case provides supporting evidence that the mTOR pathway may be important in the tumorigenesis of KS and that rapamycin may have activity in this disease.
摘要
一名66岁的患有HIV阴性经典型卡波西肉瘤的女性对雷帕霉素靶向mTOR有反应。PET-CT对该反应有充分记录。该病例提供了支持性证据，表明mTOR通路可能在卡波西肉瘤的肿瘤发生中起重要作用，且雷帕霉素可能对这种疾病有活性。
Zotero 插件