Kangani Cyrous O, Day Billy W
Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA.
Org Lett. 2008 Jul 3;10(13):2645-8. doi: 10.1021/ol800752v. Epub 2008 May 31.
A mild method for Friedel-Crafts acylation with aromatic and aliphatic carboxylic acids using cyanuric chloride, pyridine, and AlCl(3) was developed. Both inter- and intramolecular acylations were achieved at room temperature in high yield and in very short reaction times.
开发了一种使用三聚氯氰、吡啶和AlCl₃，以温和方式用芳香族和脂肪族羧酸进行傅克酰基化反应的方法。分子间和分子内酰化反应均在室温下以高产率和极短的反应时间实现。
