Strijbos Ellen, Pomp Jacqueline, Gilhuis H Jacobus
Reinier de Graaf Groep, afd. Neurologie, Delft.
Ned Tijdschr Geneeskd. 2013;157(34):A6122.
A thymoma arises from the epithelial cells of the thymus. Local tumour growth may cause symptoms like coughing, dyspnoea or chest pain. Paraneoplastic phenomena can also occur in patients with a thymoma; myasthenia gravis is a well-known example. Other neurological, dermatological, cardiological and haematological disorders are not always recognised as being paraneoplastic phenomena. There is no clear relationship between tumour activity and the clinical course of paraneoplastic phenomena. The three cases in this article illustrate how the clinical presentation of these phenomena can vary.
胸腺瘤起源于胸腺的上皮细胞。局部肿瘤生长可能会引起咳嗽、呼吸困难或胸痛等症状。胸腺瘤患者也可能出现副肿瘤综合征;重症肌无力就是一个众所周知的例子。其他神经、皮肤、心脏和血液系统疾病并不总是被认为是副肿瘤综合征。肿瘤活性与副肿瘤综合征的临床病程之间没有明确的关系。本文中的三个病例说明了这些综合征的临床表现可能会有所不同。