Faculty of Pharmacy, Federal University of Sergipe, Aracaju, Sergipe, Brazil.
Ther Clin Risk Manag. 2007 Dec;3(6):989-98.
To evaluate the impact of a Pharmaceutical Care service in the identification and resolution of drug-related problems (DRPs) and in quality of life (QoL) of a group of elderly outpatients with chronic health conditions.
30 outpatients (aged 60-75-years old) were followed between August 2003 and July 2004 at a primary health care unit in Ribeirão Preto (SP), Brazil. Patients were scheduled monthly to meet with the researcher, who provided Pharmaceutical Care service (the intervention). Through Pharmaceutical Care, the pharmacist worked with the patient and other care providers to improve outcomes of drug therapy through focused education, care planning, and monitoring. Intervention outcomes were the number of DRPs prevented or resolved, and the impact on QoL. The Short Form-36 health survey was used to measure changes in QoL.
The mean age of patients was 66 ± 5 years, 21 of whom had low literacy. During the study, 92 DRP were identified, 3.0 ± 1.5 problems per patient. By the end of the study, the interventions solved 69% of actual DRP and prevented 78.5% potential DRP. In addition, QoL showed improvement in 22 patients after DRP resolution or prevention.
Despite the limitations in this study that may affect generalizability of the results, this study demonstrates that humanistic and behavioral interventions based on the Pharmaceutical Care model were capable in reducing DRPs, and improve QoL in patients.
评估药学服务在识别和解决与药物相关问题（DRP）以及慢性病老年患者生活质量（QoL）方面的影响。
2003 年 8 月至 2004 年 7 月，在巴西里贝朗普雷图的一个初级保健单位对 30 名（60-75 岁）门诊患者进行了随访。患者每月安排与研究人员会面，由研究人员提供药学服务（干预）。通过药学服务，药剂师与患者和其他护理提供者合作，通过有针对性的教育、护理计划和监测来改善药物治疗结果。干预结果是预防或解决的 DRP 数量，以及对 QoL 的影响。采用健康调查简表（SF-36）衡量 QoL 的变化。
患者的平均年龄为 66 ± 5 岁，其中 21 人文化程度较低。在研究期间，共发现 92 例 DRP，每位患者 3.0 ± 1.5 个问题。研究结束时，干预措施解决了 92%的实际 DRP 和 78.5%的潜在 DRP。此外，在解决或预防 DRP 后，22 名患者的 QoL 得到改善。
尽管本研究存在限制，可能影响结果的普遍性，但本研究表明，基于药学服务模式的人文和行为干预措施能够减少 DRP，并改善患者的 QoL。
