Frauscher Birgit, Iranzo Alex, Högl Birgit, Casanova-Molla Jordi, Salamero Manel, Gschliesser Viola, Tolosa Eduardo, Poewe Werner, Santamaria Joan
Innsbruck Medical University, Department of Neurology, Innsbruck, Austria.
Sleep. 2008 May;31(5):724-31. doi: 10.1093/sleep/31.5.724.
The aim of our study was to determine which muscle or combination of muscles (either axial or limb muscles, lower or upper limb muscles, or proximal or distal limb muscles) provides the highest rates of rapid eye movement (REM) sleep phasic electromyographic (EMG) activity seen in patients with REM sleep behavior disorder (RBD).
Two university hospital sleep disorders centers.
Seventeen patients with idiopathic RBD (n = 8) and RBD secondary to Parkinson disease (n = 9).
Not applicable.
Patients underwent polysomnography, including EMG recording of 13 different muscles. Phasic EMG activity in REM sleep was quantified for each muscle separately. A mean of 1459.6 +/- 613.8 three-second REM sleep mini-epochs were scored per patient. Mean percentages of phasic EMG activity were mentalis (42 +/- 19), flexor digitorum superficialis (29 +/- 13), extensor digitorum brevis (23 +/- 12), abductor pollicis brevis (22 +/- 11), sternocleidomastoid (22 +/- 12), deltoid (19 +/- 11), biceps brachii (19 +/- 11), gastrocnemius (18 +/- 9), tibialis anterior (right, 17 +/- 12; left, 16 +/- 10), rectus femoris (left, 11 +/- 6; right, 9 +/- 6), and thoraco-lumbar paraspinal muscles (6 +/- 5). The mentalis muscle provided significantly higher rates of excessive phasic EMG activity than all other muscles but only detected 55% of all the mini-epochs with phasic EMG activity. Simultaneous recording of the mentalis, flexor digitorum superficialis, and extensor digitorum brevis muscles detected 82% of all mini-epochs containing phasic EMG activity. This combination provided higher rates of EMG activity than any other 3-muscle combination. Excessive phasic EMG activity was more frequent in distal than in proximal muscles, both in upper and lower limbs.
Simultaneous recording of the mentalis, flexor digitorum superficialis, and extensor digitorum brevis muscles provided the highest rates of REM sleep phasic EMG activity in subjects with RBD.
我们研究的目的是确定哪块肌肉或哪些肌肉组合（轴向肌肉或肢体肌肉、下肢或上肢肌肉、或肢体近端或远端肌肉）在快速眼动（REM）睡眠行为障碍（RBD）患者中产生最高频率的REM睡眠时相肌电图（EMG）活动。
两家大学医院睡眠障碍中心。
17例特发性RBD患者（n = 8）和帕金森病继发RBD患者（n = 9）。
不适用。
患者接受多导睡眠图检查，包括对13块不同肌肉进行肌电图记录。分别对每块肌肉在REM睡眠时的时相EMG活动进行量化。每位患者平均有1459.6±613.8个三秒的REM睡眠微时段被评分。时相EMG活动的平均百分比分别为：颏肌（42±19）、指浅屈肌（29±13）、趾短伸肌（23±12）、拇短展肌（22±11）、胸锁乳突肌（22±12）、三角肌（19±11）、肱二头肌（19±11）、腓肠肌（18±9）、胫骨前肌（右侧，17±12；左侧，16±10）、股直肌（左侧，11±6；右侧，9±6）和胸腰段椎旁肌（6±5）。颏肌产生的过度时相EMG活动频率显著高于所有其他肌肉，但仅检测到所有具有时相EMG活动的微时段中的55%。同时记录颏肌、指浅屈肌和趾短伸肌可检测到所有包含时相EMG活动的微时段中的82%。这种组合产生的EMG活动频率高于任何其他三块肌肉的组合。上肢和下肢的远端肌肉比近端肌肉出现过度时相EMG活动的频率更高。
同时记录颏肌、指浅屈肌和趾短伸肌可在RBD患者中产生最高频率的REM睡眠时相EMG活动。
