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细胞内钙动力学中幅度调制与频率调制的共存。

Coexistence of amplitude and frequency modulations in intracellular calcium dynamics.

作者信息

De Pittà Maurizio, Volman Vladislav, Levine Herbert, Pioggia Giovanni, De Rossi Danilo, Ben-Jacob Eshel

机构信息

School of Physics & Astronomy, Tel-Aviv University, 69978 Tel-Aviv, Israel.

出版信息

Phys Rev E Stat Nonlin Soft Matter Phys. 2008 Mar;77(3 Pt 1):030903. doi: 10.1103/PhysRevE.77.030903. Epub 2008 Mar 24.

DOI:10.1103/PhysRevE.77.030903
PMID:18517322
Abstract

The complex dynamics of intracellular calcium regulates cellular responses to information encoded in extracellular signals. Here we study the encoding of these external signals in the context of the Li-Rinzel model. We show that by control of biophysical parameters the information can be encoded in amplitude modulation (AM), frequency modulation (FM), or mixed (AM and FM) modulation. We briefly discuss the possible implications of this role of information encoding for astrocytes.

摘要

细胞内钙的复杂动态调节细胞对细胞外信号中编码信息的反应。在此，我们在李-林泽尔模型的背景下研究这些外部信号的编码。我们表明，通过控制生物物理参数，信息可以以调幅（AM）、调频（FM）或混合（AM和FM）调制的方式进行编码。我们简要讨论了这种信息编码作用对星形胶质细胞的可能影响。

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