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用于治疗难治性急性心力衰竭的循环支持辅助装置。

Assist devices for circulatory support in therapy-refractory acute heart failure.

作者信息

Koerner Michael M, Jahanyar Jama

机构信息

Texas Transplant Center, Department of Medicine, Section of Cardiology, University of Texas Medical Branch, Galveston, TX 77555, USA.

出版信息

Curr Opin Cardiol. 2008 Jul;23(4):399-406. doi: 10.1097/HCO.0b013e328303e134.

DOI:10.1097/HCO.0b013e328303e134
PMID:18520726
Abstract

PURPOSE OF REVIEW

Acute cardiogenic shock has a high mortality. The number of mechanical circulatory assist devices to encounter this life-threatening condition is steadily growing. These devices enable physicians to treat patients with acute cardiac failure refractory to conventional therapy. Mechanical circulatory assist devices are considered last resort to prevent or to reverse a cardiogenic shock. Different centrifugal, pulsatile or nonpulsatile (axial) flow pumps are available to rescue patients in different scenarios. These mechanical circulatory assist devices can be placed percutaneously or surgically as extracorporeal or intracorporeal mechanical circulatory assist devices.

RECENT FINDINGS

Percutaneous mechanical circulatory assist devices are useful to establish rapid life-saving circulatory support under different circumstances. A stabilized patient can then be transferred to an intensive care unit, a catheterization laboratory or an operating room for further assessment and additional treatment with possible change to a mid-term or long-term mechanical circulatory assist device.

SUMMARY

Percutaneous mechanical circulatory assist devices can be implanted in an emergency setting in patients with acute cardiogenic shock refractory to conventional therapy irrespective of the given location. The choice for a specific mechanical circulatory assist device should be based on the underlying condition and individualized prognosis. Based on the findings of this review, circulatory or axial-flow pumps should be considered first-line devices.

摘要

综述目的

急性心源性休克死亡率高。用于应对这种危及生命状况的机械循环辅助装置数量正在稳步增加。这些装置使医生能够治疗对传统疗法难治的急性心力衰竭患者。机械循环辅助装置被视为预防或逆转心源性休克的最后手段。有不同类型的离心式、搏动性或非搏动性(轴流式)泵可用于在不同情况下抢救患者。这些机械循环辅助装置可经皮或手术放置,作为体外或体内机械循环辅助装置。

最新发现

经皮机械循环辅助装置有助于在不同情况下建立快速挽救生命的循环支持。然后可将病情稳定的患者转至重症监护病房、导管室或手术室进行进一步评估和额外治疗,并可能更换为中期或长期机械循环辅助装置。

总结

对于传统疗法难治的急性心源性休克患者,无论所处位置如何,均可在紧急情况下植入经皮机械循环辅助装置。特定机械循环辅助装置的选择应基于基础病情和个体化预后。根据本综述的结果,循环泵或轴流泵应被视为一线装置。

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Curr Opin Cardiol. 2008 Jul;23(4):399-406. doi: 10.1097/HCO.0b013e328303e134.
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