Behrendt Florian F, Bruners Philipp, Keil Sebastian, Plumhans Cedric, Mahnken Andreas H, Stanzel Sven, Das Marco, Günther Rolf W, Mühlenbruch Georg
Department of Diagnostic Radiology, University Hospital, RWTH, Aachen, Germany.
Cardiovasc Intervent Radiol. 2009 Jan;32(1):25-31. doi: 10.1007/s00270-008-9359-8. Epub 2008 Jun 3.
The purpose of this study was to evaluate the influence of different peripheral vein catheter sizes on the injection pressure, flow rate, injection duration, and intravascular contrast enhancement. A flow phantom with a low-pressure venous compartment and a high-pressure arterial compartment simulating physiological circulation parameters was used. High-iodine-concentration contrast medium (370 mg iodine/ml; Ultravist 370) was administered in the venous compartment through peripheral vein catheters of different sizes (14, 16, 18, 20, 22, and 24 G) using a double-head power injector with a pressure limit of 325 psi. The flow rate was set to 5 ml/s, with a total iodine load of 36 g for all protocols. Serial CT scans at the level of the pulmonary artery and the ascending and the descending aorta replica were obtained. The true injection flow rate, injection pressure, injection duration, true contrast material volume, and pressure in the phantom during and after injection were continuously monitored. Time enhancement curves were computed and both pulmonary and aortic peak time and peak enhancement were determined. Using peripheral vein catheters with sizes of 14-20 G, flow rates of approximately 5 ml/s were obtained. During injection through a 22-G catheter the pressure limit was reached and the flow rate was decreased, with a consecutive decreased pulmonary and aortic contrast enhancement compared to the 14- to 20-G catheters. Injection through a 24-G peripheral vein catheter was not possible because of disconnection of the canula due to the high flow rate and pressure. In summary, intravenous catheters with sizes of 14-20 G are suitable for CT angiography using an injection protocol with a high flow rate and a high-iodine-concentration contrast medium.
本研究的目的是评估不同外周静脉导管尺寸对注射压力、流速、注射持续时间和血管内造影剂增强的影响。使用了一种模拟生理循环参数的具有低压静脉腔和高压动脉腔的流动模型。通过不同尺寸（14、16、18、20、22和24G）的外周静脉导管，在静脉腔内使用压力限制为325磅力/平方英寸的双头动力注射器注入高碘浓度造影剂（370毫克碘/毫升；优维显370）。流速设定为5毫升/秒，所有方案的总碘负荷为36克。在肺动脉水平以及升主动脉和降主动脉模型处进行连续CT扫描。连续监测真实注射流速、注射压力、注射持续时间、真实造影剂体积以及注射期间和注射后模型中的压力。计算时间增强曲线，并确定肺和主动脉的峰值时间和峰值增强。使用14 - 20G尺寸的外周静脉导管可获得约5毫升/秒的流速。通过22G导管注射时达到了压力限制，流速降低，与14 - 20G导管相比，肺和主动脉的造影剂增强连续下降。由于高流速和压力导致套管断开，无法通过24G外周静脉导管进行注射。总之，14 - 20G尺寸的静脉导管适用于使用高流速和高碘浓度造影剂注射方案的CT血管造影。
