W. M. Keck Biomedical Materials Research Lab, School of Mechanical and Materials Engineering, Washington State University, Pullman, WA 99164-2920, USA.
J Mater Sci Mater Med. 2009 Dec;20 Suppl 1:S29-34. doi: 10.1007/s10856-008-3478-2. Epub 2008 Jun 3.
Fabrication of net shape load bearing implants with complex anatomical shapes to meet desired mechanical and biological performance is still a challenge. In this article, an overview of our research activities is discussed focusing on application of Laser Engineered Net Shaping (LENS) toward load bearing implants to increase in vivo life time. We have demonstrated that LENS can fabricate net shape, complex metallic implants with designed porosities up to 70 vol.% to reduce stress-shielding. The effective modulus of Ti, NiTi, and other alloys was tailored to suit the modulus of human cortical bone by introducing 12-42 vol.% porosity. In addition, laser processed porous NiTi alloy samples show a 2-4% recoverable strain, a potentially significant result for load bearing implants. To minimize the wear induced osteolysis, unitized structures with functionally graded Co-Cr-Mo coating on porous Ti6Al4V were also made using LENS, which showed high hardness with excellent bone cell-materials interactions. Finally, LENS is also being used to fabricate porous, net shape implants with a functional gradation in porosity characteristics.
制造具有复杂解剖形状的、满足所需机械和生物性能的净成型承重植入物仍然是一个挑战。本文讨论了我们的研究活动概述，重点介绍了激光工程网成型（LENS）在承重植入物中的应用，以提高体内寿命。我们已经证明，LENS 可以制造具有设计孔隙率高达 70 体积%的净成型、复杂金属植入物，以减少应力屏蔽。通过引入 12-42 体积%的孔隙率，可以将 Ti、NiTi 和其他合金的有效模量调整为适合人皮质骨的模量。此外，激光加工的多孔 NiTi 合金样品显示出 2-4%的可恢复应变，这对于承重植入物来说是一个潜在的重要结果。为了最大限度地减少磨损引起的骨溶解，还使用 LENS 在多孔 Ti6Al4V 上制造了具有功能梯度 Co-Cr-Mo 涂层的整体结构，该结构具有高硬度和优异的骨细胞材料相互作用。最后，LENS 还用于制造具有孔隙率特征功能梯度的多孔、净成型植入物。
Zotero 插件