Mateu C, Haro G, Barabash A, Benito A, Calatayud M, Traver F
Unidad de Conductas Adictivas y Patología Dual. Servicio de Psiquiatría. Hospital de La Ribera. Alzira (Valencia), Spain.
Actas Esp Psiquiatr. 2008 Jul-Aug;36(4):230-43.
The most important bibliography on the role of genetics in personality and its disorders has been reviewed from a clinical point of view. Following the introduction, the most relevant findings on genetics and the personality dimensions are compiled, focusing on Cloninger's Psychobiological Model. Regarding personality disorder, studies have been found on cluster A, mainly related to the schizotypal personality disorder, and on cluster B, mainly related to antisocial personality and borderline disorders. The bibliography on cluster C PD was limited. The review concludes with a discussion that stresses the possible usefulness of personality dimensions, considered as interphenotypes regarding both diagnostic aspects and treatment.
已从临床角度对关于遗传学在人格及其障碍中作用的最重要文献进行了综述。引言之后，汇编了关于遗传学和人格维度的最相关研究结果，重点是克隆宁格的心理生物学模型。关于人格障碍，已发现对A类群的研究，主要与分裂型人格障碍有关，以及对B类群的研究，主要与反社会人格和边缘型障碍有关。关于C类人格障碍的文献有限。综述最后进行了讨论，强调了人格维度在诊断和治疗方面作为中间表型可能具有的有用性。
