Chang Henry L, Rosenberg Andrew E, Friedmann Alison M, Ryan Daniel P, Masiakos Peter T
Division of Pediatric Surgery, Department of Surgery, Department of Pediatrics, Massachusetts General Hospital, Boston, MA, USA.
J Pediatr Hematol Oncol. 2008 Jun;30(6):461-3. doi: 10.1097/MPH.0b013e318165b2b1.
Primary pulmonary rhabdomyosarcoma (RMS) in the pediatric population is a rare entity. A 5-month-old boy initially treated for pneumonia was proven to have a primary pulmonary RMS, which was resected via thoracotomy. After a course of chemotherapy following the Children's Oncology Group low-risk RMS protocol (ARST0331), a restaging chest computerized tomography scan showed local recurrence, which was also resected by open thoracotomy. The patient is currently undergoing local radiotherapy and salvage chemotherapy regimen. This patient is the youngest reported to date with this entity. The prognostic significance of his young age and the morphologic findings of his tumor are unclear.
小儿原发性肺横纹肌肉瘤（RMS）是一种罕见的疾病。一名5个月大的男童最初因肺炎接受治疗，后来被证实患有原发性肺RMS，通过开胸手术将其切除。按照儿童肿瘤学组低风险RMS方案（ARST0331）进行了一个疗程的化疗后，重新分期的胸部计算机断层扫描显示局部复发，再次通过开胸手术切除。该患者目前正在接受局部放疗和挽救性化疗方案。该患者是迄今为止报道的患此疾病年龄最小的。其年幼的年龄和肿瘤的形态学表现的预后意义尚不清楚。
