Zeisler H, Mayerhofer K, Joura E A, Bancher-Todesca D, Kainz C, Breitenecker G, Reinthaller A
Department of Gynecology and Obstetrics, University of Vienna Medical School, Austria.
Gynecol Oncol. 1998 Apr;69(1):78-83. doi: 10.1006/gyno.1998.4962.
Embryonal rhabdomyosarcoma (RMS) of the female genital tract usually occurs during childhood in the vagina. In rare cases, RMS can originate in the uterine cervix, with a peak incidence in the second decade. A combined modality approach to treating RMS using multidrug chemotherapy, radiotherapy, and surgery has markedly improved survival. Early stage embryonal RMS of the cervix has been found to have an excellent prognosis. The present case and literature review indicate that extensive surgery does not improve survival in patients with stage I disease.
女性生殖道胚胎性横纹肌肉瘤(RMS)通常发生于儿童期的阴道。在罕见情况下,RMS可起源于子宫颈,发病高峰在第二个十年。采用多药化疗、放疗和手术联合治疗RMS的方法显著提高了生存率。已发现早期子宫颈胚胎性RMS预后良好。本病例及文献综述表明,广泛手术并不能提高I期疾病患者的生存率。