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已缓解的乙型肝炎病毒感染的晚期再激活:基于利妥昔单抗方案治疗后日益增加的并发症?

Late reactivation of resolved hepatitis B virus infection: an increasing complication post rituximab-based regimens treatment?

作者信息

Garcia-Rodriguez Maria J, Canales Miguel A, Hernandez-Maraver Dolores, Hernandez-Navarro Fernando

机构信息

Servicio de Hematologia, Hospital Universitario La Paz, Madrid, Spain.

出版信息

Am J Hematol. 2008 Aug;83(8):673-5. doi: 10.1002/ajh.21214.

DOI:10.1002/ajh.21214
PMID:18528824
Abstract

Reactivation of hepatitis B infection is an increasing problem for patients with lymphoma, even in resolved infections, who were treated with rituximab-based regimens. Our cases point out the need of prolonged prophylaxis in HBsAg-negative patients due to the high risk of developing fatal reactivation.

摘要

对于淋巴瘤患者,即使是已治愈的感染患者,使用基于利妥昔单抗的方案治疗后,乙型肝炎病毒感染再激活仍是一个日益严重的问题。我们的病例指出,由于发生致命性再激活的风险很高,HBsAg阴性患者需要延长预防措施。

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Late reactivation of resolved hepatitis B virus infection: an increasing complication post rituximab-based regimens treatment?已缓解的乙型肝炎病毒感染的晚期再激活:基于利妥昔单抗方案治疗后日益增加的并发症?
Am J Hematol. 2008 Aug;83(8):673-5. doi: 10.1002/ajh.21214.
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Reactivation of hepatitis B virus following rituximab-based regimens: a serious complication in both HBsAg-positive and HBsAg-negative patients.基于利妥昔单抗方案治疗后乙肝病毒再激活:HBsAg阳性和HBsAg阴性患者的严重并发症
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