Garcia-Rodriguez Maria J, Canales Miguel A, Hernandez-Maraver Dolores, Hernandez-Navarro Fernando
Servicio de Hematologia, Hospital Universitario La Paz, Madrid, Spain.
Am J Hematol. 2008 Aug;83(8):673-5. doi: 10.1002/ajh.21214.
Reactivation of hepatitis B infection is an increasing problem for patients with lymphoma, even in resolved infections, who were treated with rituximab-based regimens. Our cases point out the need of prolonged prophylaxis in HBsAg-negative patients due to the high risk of developing fatal reactivation.
对于淋巴瘤患者,即使是已治愈的感染患者,使用基于利妥昔单抗的方案治疗后,乙型肝炎病毒感染再激活仍是一个日益严重的问题。我们的病例指出,由于发生致命性再激活的风险很高,HBsAg阴性患者需要延长预防措施。