Michaud P, Michenet P, Lemaire B, Maitre F, Tescher M
Service de Gynécologie-Obstétrique A, Hôpital Général, Orléans.
Rev Fr Gynecol Obstet. 1991 Mar;86(3):225-8.
Placental villitis, which is defined by the presence of lymphocytic or macrophagic inflammatory cells within the villosities, constitutes a recently-described histopathological entity. This condition is the consequence of an immune response of the feto-placental unit towards a non-specific, multiple aggression and the incidence is very low. The extent of the inflammatory reaction may culminate in placentitis, resulting in miscarriage. Although a large number of infecting agents are known to be responsible for the pathogenesis of villitis, in most cases the etiology remains unknown. The hypothesis of a failure of the mechanisms of immunotolerance during pregnancy is suggested by many authors to explain their origin.
胎盘绒毛炎是指绒毛内存在淋巴细胞或巨噬细胞性炎症细胞，是一种最近才被描述的组织病理学实体。这种情况是胎儿 - 胎盘单位对非特异性、多重侵袭产生免疫反应的结果，发病率很低。炎症反应的程度可能最终导致胎盘炎，从而导致流产。虽然已知大量感染因子是绒毛炎发病机制的原因，但在大多数情况下，病因仍然不明。许多作者提出妊娠期间免疫耐受机制失败的假说以解释其起源。
