Podolak-Dawidziak M
Department of Haematology, Medical Academy, Wrocław, Poland.
Thromb Res. 1991 Apr;62(1-2):93-6. doi: 10.1016/0049-3848(91)90672-j.
Megakaryocyte colony formation was increased in 13 patients with ITP. Out of splenectomized ITP patients Colony Forming Unit-Megakaryocyte (CFU-Mk) number normalized in four but was lower than normal in the remaining two. The proportion of immature megakaryocytes was higher in ITP than in normals or in ITP patients after splenectomy. In conclusion, in ITP accelerated platelet destruction leads to stimulation of megakaryocytopoiesis, but some features of its ineffectiveness can be observed.
13例免疫性血小板减少症（ITP）患者的巨核细胞集落形成增加。在脾切除的ITP患者中，四例的巨核细胞集落形成单位（CFU-Mk）数量恢复正常，但其余两例低于正常水平。ITP患者中未成熟巨核细胞的比例高于正常人和脾切除后的ITP患者。总之，在ITP中，血小板破坏加速导致巨核细胞生成受到刺激，但可以观察到其无效性的一些特征。
