Ono Shouko, Kato Mototsugu, Ono Yuji, Itoh Tomoo, Kubota Kanako, Nakagawa Manabu, Shimizu Yuichi, Asaka Masahiro
Division of Endoscopy, Hokkaido University Hospital, Sapporo, Japan.
Gastrointest Endosc. 2008 Oct;68(4):624-31. doi: 10.1016/j.gie.2008.02.066. Epub 2008 Jun 5.
The utility of magnifying endoscopy for diagnosis of epithelial tumors has been reported, but there are few reports for nonepithelial tumors.
To determine the characteristics of magnified images of gastric extranodal marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue (MALT lymphoma) before and after treatment.
This was a retrospective study.
Endoscopy Unit, Hokkaido University Hospital.
Eleven patients diagnosed with MALT lymphoma were enrolled.
The microstructural pattern, collecting venules, and abnormal vessels in gastric MALT lymphoma were assessed before treatment and at 4 to 7 months after treatment by using magnifying endoscopy. MAIN OUTCOME MEASUREMENT AND RESULTS: The characteristics of magnified endoscopic images before treatment were the disappearance of gastric pits and the appearance of abnormal vessels. Ten cases of Helicobacter pylori-infected MALT lymphoma were treated by H. pylori eradication, and 1 H. pylori-negative case was treated by radiation therapy after eradication therapy. Ten patients achieved complete disease remission. After the treatment, recovery of gastric pits and subepithelial capillary network, and the disappearance of abnormal vessels were revealed by magnifying endoscopy.
This was a small pilot study.
Magnified findings of gastric MALT lymphoma before and after therapy seem to correlate with complete response and no response.
放大内镜在诊断上皮性肿瘤方面的应用已有报道，但关于非上皮性肿瘤的报道较少。
确定黏膜相关淋巴组织胃外边缘区B细胞淋巴瘤（MALT淋巴瘤）治疗前后放大图像的特征。
这是一项回顾性研究。
北海道大学医院内镜科。
纳入11例诊断为MALT淋巴瘤的患者。
采用放大内镜在治疗前以及治疗后4至7个月评估胃MALT淋巴瘤的微观结构模式、集合小静脉和异常血管。
治疗前放大内镜图像的特征为胃小凹消失和异常血管出现。10例幽门螺杆菌感染的MALT淋巴瘤患者接受了幽门螺杆菌根除治疗，1例幽门螺杆菌阴性患者在根除治疗后接受了放射治疗。10例患者实现了疾病完全缓解。治疗后，放大内镜显示胃小凹和上皮下毛细血管网恢复，异常血管消失。
这是一项小型初步研究。
胃MALT淋巴瘤治疗前后的放大表现似乎与完全缓解和无反应相关。
