Hassegawa Renato Takayuki, Ogawa Eduardo Koji Marchi, El Ibrahim Roberto, Venco Filadelfio Euclides, Maruta Luis Masuo
Universidade de São Paulo (USP), Hospital Universitário, Endoscopy Service. São Paulo, SP, Brazil.
Universidade de São Paulo (USP), Hospital das Clínicas, Endoscopy Service. São Paulo, SP, Brazil.
Autops Case Rep. 2019 Dec 13;10(1):e2019130. doi: 10.4322/acr.2019.130. eCollection 2020 Jan-Mar.
Mucosa-associated lymphoid tissue (MALT) lymphoma is the most common type of extra-nodal non-Hodgkin lymphoma, which mostly involves the stomach. The clinical suspicion and diagnosis are often challenging because of the lack of specific symptoms and conventional endoscopic findings. Three magnifying endoscopic signs of the gastric mucosa have been described as highly specific to the diagnosis of MALT lymphoma, such as (i) tree-like appearance of the microvessels; (ii) non-structural area; and (iii) ballooning crypt pattern. We report the case of a middle-aged woman in which these signs appeared chronologically over a period of 2 years, showing the association of the sequence of the endoscopic findings and the final histological diagnosis of gastric MALT lymphoma.
黏膜相关淋巴组织（MALT）淋巴瘤是最常见的结外非霍奇金淋巴瘤类型，主要累及胃部。由于缺乏特异性症状和传统内镜检查结果，临床怀疑和诊断往往具有挑战性。胃黏膜的三种放大内镜征象已被描述为对MALT淋巴瘤的诊断具有高度特异性，例如：（i）微血管呈树状外观；（ii）无结构区域；（iii）隐窝膨胀模式。我们报告了一例中年女性病例，这些征象在2年的时间里按时间顺序出现，显示了内镜检查结果序列与胃MALT淋巴瘤最终组织学诊断之间的关联。
