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黏膜相关淋巴组织淋巴瘤的眼眶、腹膜后和胸膜同时性病变:病例报告。

Metachronous lesions in the orbit, retroperitoneum, and pleura of mucosa-associated lymphoid tissue lymphoma: A case report.

机构信息

Department of Respiratory Medicine, Comprehensive Cancer Center, International Medical Center, Saitama Medical University, Hidaka, Japan.

Department of Pathology, Comprehensive Cancer Center, International Medical Center, Saitama Medical University, Hidaka, Japan.

出版信息

Cancer Rep (Hoboken). 2022 Oct;5(10):e1689. doi: 10.1002/cnr2.1689. Epub 2022 Jul 28.

DOI:10.1002/cnr2.1689
PMID:35899993
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9575486/
Abstract

BACKGROUND

Mucosa associated lymphoid tissue (MALT) lymphoma of the orbit is rare, often indolent, but can recur, and spread to extra-nodal sites. Pleural and retroperitoneum recurrences of MALT lymphoma are rare.

CASE

A 65-year-old man was referred to our hospital due to right pleural effusion and difficulty in breathing. He had a medical history of having undergone surgery for MALT lymphoma of the left orbit. A chest computed tomography (CT) scan showed right pleural thickness, pleural effusion, and a retroperitoneal mass, spreading from the muscular layer to the subcutaneous layer. The thickened pleural lesion was surgically biopsied and diagnosed as a recurrence of MALT lymphoma.

CONCLUSION

Pleural effusion should be carefully examined and monitored for the possibility of recurrence in MALT lymphoma patients.

摘要

背景

眼附属淋巴组织(MALT)淋巴瘤较为罕见,通常为惰性,但可复发并扩散至结外部位。MALT 淋巴瘤胸膜和腹膜后复发较为罕见。

病例

一名 65 岁男性因右侧胸腔积液和呼吸困难被转诊至我院。他曾有左眼 MALT 淋巴瘤手术史。胸部计算机断层扫描(CT)显示右侧胸腔增厚、胸腔积液和腹膜后肿块,从肌肉层向皮下层扩散。增厚的胸膜病变被手术活检,并诊断为 MALT 淋巴瘤复发。

结论

对于 MALT 淋巴瘤患者,应仔细检查胸腔积液并监测其复发的可能性。

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Recurrence of Gastric Mucosa-associated Lymphoid Tissue Lymphoma in the Pleura: A Case Report.
Cureus. 2019 Jul 16;11(7):e5150. doi: 10.7759/cureus.5150.
2
Pulmonary extranodal marginal zone lymphoma that presented with macroglobulinemia and marked plasmacytic cell proliferation carrying the t(14;18)(q32;q21)/MALT1-immunoglobulin heavy-chain fusion gene in pleural fluid.伴有巨球蛋白血症及显著浆细胞增殖的肺结外边缘区淋巴瘤,其胸腔积液中携带t(14;18)(q32;q21)/MALT1-免疫球蛋白重链融合基因
J Clin Exp Hematop. 2018 Sep 19;58(3):141-147. doi: 10.3960/jslrt.18013. Epub 2018 Aug 8.
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Lymphoproliferative Disorders of the Lung.肺部淋巴组织增生性疾病。
Respiration. 2017;94(2):157-175. doi: 10.1159/000477740. Epub 2017 Jun 14.
4
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Int J Hematol. 2010 Sep;92(2):369-73. doi: 10.1007/s12185-010-0645-2. Epub 2010 Aug 20.
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Clinical characteristics and prognostic factors of pulmonary MALT lymphoma.肺黏膜相关淋巴组织淋巴瘤的临床特征和预后因素。
Eur Respir J. 2009 Dec;34(6):1408-16. doi: 10.1183/09031936.00039309. Epub 2009 Jun 18.
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Ann Nucl Med. 2008 May;22(4):261-7. doi: 10.1007/s12149-007-0125-9. Epub 2008 Jun 6.
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Chest. 2008 Feb;133(2):433-40. doi: 10.1378/chest.07-1956. Epub 2007 Dec 10.
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