Zhang J Z, Shen Y G, Zhang X X
Key Laboratory for Thermal Science and Power Engineering of the Ministry of Education, Department of Thermal Engineering, Tsinghua University, Beijing, 100084, People's Republic of China.
Lasers Med Sci. 2009 May;24(3):329-38. doi: 10.1007/s10103-008-0566-y. Epub 2008 Jun 7.
A dynamic photo-thermal model of carbon dioxide (CO(2)) laser tissue ablation was developed, based on McKenzie's three-zone model, with the following improvements: (1) the laser-irradiated tissue from the surface to the inside was divided into a carbonized zone, a dried zone, a dehydrating zone, a thermally damaged wet (TDW) zone and an uncoagulated zone; (2) the carbonized and dried tissues were analyzed as porous media, with convection heat transfer between the vapor from the dehydrating tissue and the porous dried/carbonized tissue taken into account; (3) the interactions of temperature distribution, deposited laser energy distribution and dynamic changes in optical and thermal properties as well as blood perfusion rate were included. The finite difference method was used to solve numerically for the temperature and deposited laser energy fields, and the boundary positions of the zones.
基于麦肯齐的三区模型,开发了一种二氧化碳(CO₂)激光组织消融的动态光热模型,并做了以下改进:(1)从表面到内部的激光照射组织被分为碳化区、干燥区、脱水区、热损伤湿区(TDW)和未凝固区;(2)将碳化和干燥组织作为多孔介质进行分析,考虑了脱水组织产生的蒸汽与多孔干燥/碳化组织之间的对流热传递;(3)纳入了温度分布、沉积激光能量分布以及光学和热学性质及血液灌注率的动态变化之间的相互作用。采用有限差分法对温度场、沉积激光能量场以及各区域的边界位置进行数值求解。