Nishida M
Department of Obstetrics and Gynecology, Tsukuba University, Ibaraki, Japan.
Am J Obstet Gynecol. 1991 Jul;165(1):229-31. doi: 10.1016/0002-9378(91)90257-r.
An attempt was made to evaluate the relationship between histologic findings of adenomyosis and onset of dysmenorrhea. Thirty-four cases of histologically diagnosed adenomyosis were investigated in this study. One large sample cut along the longitudinal axis was made and examined to evaluate the histologic parameters and CA 125 levels. Dysmenorrhea was classified into grade I (absent or mild) and grade II (severe). Localization of adenomyosis was divided into type I, adenomyosis continuous from the surface endometrium (29 cases), and type II, adenomyosis present on the serous side of the uterus and not continuous from the surface endometrium (five cases). We made type I adenomyosis, which included 13 cases of grade I and 16 cases of grade II, the focus of our investigation. The parameters that correlated with dysmenorrhea were the number of islands of adenomyosis and glands, distance of invasion, relative rate of invasion, and CA 125 levels. The differences between grades I and II were apparent in the frequency distribution tables, with dysmenorrhea occurring at invasion rates of 80% and greater.
本研究旨在评估子宫腺肌病的组织学表现与痛经发作之间的关系。本研究调查了34例经组织学诊断为子宫腺肌病的病例。制作一个沿纵轴切开的大样本并进行检查，以评估组织学参数和CA 125水平。痛经分为I级（无或轻度）和II级（重度）。子宫腺肌病的定位分为I型，即从表面子宫内膜连续的子宫腺肌病（29例），和II型，即存在于子宫浆膜侧且与表面子宫内膜不连续的子宫腺肌病（5例）。我们将I型子宫腺肌病作为研究重点，其中包括13例I级和16例II级。与痛经相关的参数有子宫腺肌病岛和腺体数量、浸润距离、相对浸润率以及CA 125水平。I级和II级之间的差异在频率分布表中很明显，痛经发生在浸润率达到80%及更高时。
