Creasman W T, DiSaia P J
Department of Obstetrics and Gynecology, Medical University of South Carolina, Charleston 29425.
Am J Obstet Gynecol. 1991 Jul;165(1):7-10. doi: 10.1016/0002-9378(91)90213-b.
Ovarian cancer will affect 20,000 American women this year and some 13,500 will die of the disease. Most patients will have stage III or IV disease at the time of diagnosis. Because ovarian cancer may be initially without symptoms, attempts have been made to develop screening tests that would lead to an early diagnosis. Two tests, serum CA 125 and pelvic ultrasonography, have been suggested by some to be accurate enough to be included in yearly screening for ovarian cancer. Although further testing of these techniques is encouraged, data to date do not justify yearly screening with CA 125 or pelvic ultrasonography in all women.
今年，美国将有2万名女性罹患卵巢癌，其中约1.35万人会死于该疾病。大多数患者在确诊时已处于III期或IV期。由于卵巢癌最初可能没有症状，因此人们一直在尝试开发能够实现早期诊断的筛查测试。一些人建议，血清CA 125和盆腔超声检查这两项测试准确性足以纳入卵巢癌年度筛查。尽管鼓励对这些技术进行进一步测试，但迄今为止的数据并不支持对所有女性进行CA 125或盆腔超声检查的年度筛查。
