Ringbaek T, Brøndum E, Martinez G, Lange P
Department of Respiratory Medicine and Cardiology, University Hospital of Copenhagen, Hvidovre, Denmark.
Chron Respir Dis. 2008;5(2):75-80. doi: 10.1177/1479972307087366.
Pulmonary rehabilitation in chronic obstructive pulmonary disease (COPD) improves exercise tolerance and health status, however, these effects have been shown to decline after termination of the rehabilitation program. This study has examined the long-term effect of a 7-week supervised rehabilitation program combined with daily self-monitored training at home on exercise tolerance and health status. Two hundred and nine consecutive COPD patients who had completed a 7-week pulmonary rehabilitation program were assessed with endurance shuttle walk test (ESWT) and the St George's Respiratory Questionnaire (SGRQ) at baseline, 0, 3, and 12 months after the program. Sixty-eight (32.5%) patients did not attend the 1-year follow-up. Among the 141 patients who competed the 1-year evaluation, the initial improvement after the 7-week program in the ESWT time was 180 s or 101% (p = 0.001) and in SGRQ 3.4 units (p = 0.001). These effects were maintained at the 1-year evaluation (ESWT 59% above baseline; p < 0.001 and improved SGRQ 3.0 units compared with baseline; p = 0.011). The 31 patients who attended the 6-month, but not the 12-month evaluation, improved ESWT time by 96 s (p = 0.02) without any change in SGRQ +2.0 (p = 0.40). A relative simple and inexpensive 7-week supervised rehabilitation program combined with daily self-monitored training at home was able to maintain significant improvement in exercise tolerance and health status throughout 1 year. Death and hospital admissions due to acute exacerbations were the main reasons for non-attendance in the follow-up period.
慢性阻塞性肺疾病(COPD)的肺康复可提高运动耐力和健康状况,然而,这些效果在康复计划终止后会逐渐下降。本研究探讨了一项为期7周的有监督康复计划结合每日在家自我监测训练对运动耐力和健康状况和健康状况的长期影响。对209例连续完成7周肺康复计划的COPD患者,在计划开始时、结束时、结束后3个月和12个月,采用耐力穿梭步行试验(ESWT)和圣乔治呼吸问卷(SGRQ)进行评估。68例(32.5%)患者未参加1年随访。在完成1年评估的141例患者中,7周计划后ESWT时间的初始改善为180秒或101%(p = 0.001),SGRQ改善3.4个单位(p = 0.001)。这些效果在1年评估时得以维持(ESWT比基线高59%;p < 0.001,SGRQ与基线相比改善3.0个单位;p = 0.011)。31例参加了6个月但未参加12个月评估的患者,ESWT时间改善了96秒(p = 0.02),SGRQ无变化(+2.0,p = 0.40)。一项相对简单且费用低廉的为期7周的有监督康复计划结合每日在家自我监测训练能够在1年内持续显著改善运动耐力和健康状况。死亡和因急性加重住院是随访期间未参加的主要原因。