Kim Brian, Garcia Francisco, Touma Naji, Moussa Madeleine, Izawa Jonathan I
Department of Medical Education, Faculty of Medicine, University of Toronto, Toronto, Ont.
Can Urol Assoc J. 2007 Nov;1(4):404-7. doi: 10.5489/cuaj.458.
Penile carcinoma in situ, or Queyrat's erythroplasia, is a rare condition of the glans penis. This lesion has been associated with invasive squamous cell carcinoma; however, metastasis without an invasive component is extremely rare. There have only been 2 documented cases with metachronous metastases. We report a third case in which metastases were diagnosed at presentation. The patient was a 51-year-old man who presented with a glans penile lesion and bilateral inguinal masses later determined to be carcinoma in situ with metastases to the inguinal and pelvic lymph nodes. He subsequently underwent a partial penectomy and lymphadenectomy followed by adjuvant chemotherapy and radiation. This case is discussed, along with a brief review of the literature.
阴茎原位癌，即凯腊增殖性红斑，是一种阴茎头的罕见病症。该病变与浸润性鳞状细胞癌相关；然而，无浸润成分的转移极为罕见。仅有2例有记录的异时性转移病例。我们报告第3例在初诊时即诊断出转移的病例。患者为一名51岁男性，其阴茎头有病变，双侧腹股沟肿块后来确定为原位癌并伴有腹股沟和盆腔淋巴结转移。他随后接受了阴茎部分切除术和淋巴结清扫术，之后进行了辅助化疗和放疗。本文讨论了该病例，并对文献进行了简要回顾。
