Payne C G, Edbrooke D L, Davies G K
Department of Anaesthetics, Royal Hallamshire Hospital, Sheffield, U.K.
Arch Emerg Med. 1991 Mar;8(1):24-32. doi: 10.1136/emj.8.1.24.
The efficacy of Entonox as a supplement to local anaesthesia for minor surgical procedures was studied. Eighty-five patients undergoing surgery for the incision and drainage of a subcutaneous abscess using a local anaesthetic were involved in a trial to ascertain the level of pain associated with such procedures and to investigate the possibility of using on-demand Entonox to supplement the local anaesthesia provided. Patients received either the standard local anaesthesia, or, alternatively, the local anaesthesia was supplemented with oxygen or Entonox via on-demand apparatus. Patients indicated on three linear visual analogue scales their pain, anxiety and total discomfort, and also on a cartoon pain rating scale, at different stages during the operation. Results showed that there was no statistically significant reduction in pain provided by the Entonox, despite general patient approval. Both oxygen and Entonox showed some anxiolytic properties. Pure oxygen was also seen to produce a rise in heart rate, while both gases (pure oxygen and Entonox) caused an increase in diastolic blood pressure. It was also seen that the patient's short term memory of the pain experienced was unaffected by pure oxygen or Entonox.
研究了恩托诺克斯(Entonox)作为局部麻醉辅助手段用于小型外科手术的疗效。85名使用局部麻醉进行皮下脓肿切开引流手术的患者参与了一项试验,以确定此类手术相关的疼痛程度,并研究使用按需提供的恩托诺克斯补充局部麻醉的可能性。患者接受标准局部麻醉,或者通过按需装置用氧气或恩托诺克斯补充局部麻醉。患者在手术的不同阶段通过三个线性视觉模拟量表表明其疼痛、焦虑和总体不适程度,还通过卡通疼痛评分量表进行评分。结果显示,尽管患者普遍认可,但恩托诺克斯并未使疼痛得到统计学上的显著减轻。氧气和恩托诺克斯均显示出一定的抗焦虑特性。还观察到纯氧会使心率升高,而两种气体(纯氧和恩托诺克斯)都会导致舒张压升高。还发现患者对所经历疼痛的短期记忆不受纯氧或恩托诺克斯的影响。