Missotten P, Squelard G, Ylieff M, Di Notte D, Paquay L, De Lepeleire J, Buntinx F, Fontaine O
Clinical Psychology of Ageing, Qualidem Research Project, University of Liège, Liège, Belgium.
Dement Geriatr Cogn Disord. 2008;25(6):564-72. doi: 10.1159/000137689. Epub 2008 Jun 11.
We aimed to examine the association of cognitive decline with quality of life (QoL) in dementia compared to controls and to determine variables associated with QoL.
Every subject was placed within a specific group depending on their designation by the Mini Mental State Examination and evaluated by the Alzheimer's Disease Related Quality of Life (ADRQL) and clinical assessments.
QoL for the mild dementia group was lower (p = 0.08) than that of controls. The very severe dementia group had a significantly lower QoL than the other dementia groups, which all had similar ADRQL scores. The only predictor of ADRQL scores was found to be the behavioral and psychological symptoms of dementia.
There is no direct relationship between cognitive decline and QoL.
我们旨在研究与对照组相比，痴呆症患者认知功能衰退与生活质量（QoL）之间的关联，并确定与生活质量相关的变量。
根据简易精神状态检查表的评定，将每位受试者分入特定组别，并通过阿尔茨海默病相关生活质量量表（ADRQL）和临床评估进行评价。
轻度痴呆组的生活质量低于对照组（p = 0.08）。极重度痴呆组的生活质量显著低于其他痴呆组，而其他痴呆组的ADRQL评分相似。结果发现，ADRQL评分的唯一预测因素是痴呆的行为和心理症状。
认知功能衰退与生活质量之间不存在直接关系。
