帕金森病患者中重度抑郁症诊断的准确性：统一帕金森病评定量表、老年抑郁量表和贝克抑郁量表的比较研究
The accuracy of diagnosis of major depression in patients with Parkinson's disease: a comparative study among the UPDRS, the geriatric depression scale and the Beck depression inventory.
作者信息
Tumas Vitor, Rodrigues Guilherme Gustavo Ricioppo, Farias Tarsis Leonardo Almeida, Crippa José Alexandre S
机构信息
Department of Neurology, Psychatry and Medical Psychology, Ribeirão Preto School of Medicine, University of São Paulo, Brazil.
出版信息
Arq Neuropsiquiatr. 2008 Jun;66(2A):152-6. doi: 10.1590/s0004-282x2008000200002.
OBJECTIVE
Evaluate the accuracy of diagnosis of major depression in patients with Parkinson's disease (PD) using the UPDRS, the 15-item Geriatric Depression Scale (GDS15) and the Beck Depression Inventory (BDI).
METHOD
50 consecutive patients with PD were evaluated. The diagnosis of major depression was made according to the DSM-IV criteria.
RESULTS
We found a 24% prevalence of major depression. All depression scales were highly correlated but UPDRS depression item had the lowest diagnostic value. The GDS15 had the more appropriate "receiver operating characteristics" curve. The best cut-off scores for screening depression were 17/18 for BDI and 8/9 for GDS15. We did not find any correlation between the level of depression and intensity of motor symptoms, functional capacity and duration of the disease.
CONCLUSION
GDS15 is better than the BDI and the UPDRS for screening depression in PD and depression is not related to the degree of parkinsonian symptoms.
目的
使用统一帕金森病评定量表（UPDRS）、15项老年抑郁量表（GDS15）和贝克抑郁量表（BDI）评估帕金森病（PD）患者中重度抑郁症的诊断准确性。
方法
对50例连续的PD患者进行评估。根据《精神疾病诊断与统计手册》第四版（DSM-IV）标准诊断重度抑郁症。
结果
我们发现重度抑郁症的患病率为24%。所有抑郁量表相关性都很高，但UPDRS抑郁项目的诊断价值最低。GDS15具有更合适的“受试者工作特征”曲线。筛查抑郁症的最佳临界值，BDI为17/18，GDS15为8/9。我们未发现抑郁程度与运动症状强度、功能能力和病程之间存在任何相关性。
结论
在PD患者中筛查抑郁症时，GDS15比BDI和UPDRS更好，且抑郁症与帕金森症状的严重程度无关。
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