Massai Perla, Colalelli Francesca, Sansoni Julita, Valente Donatella, Tofani Marco, Fabbrini Giovanni, Fabbrini Andrea, Scuccimarri Michela, Galeoto Giovanni
Sapienza University of Rome, Rome, Italy.
Department of Public Health and Infection Disease, Sapienza University of Rome, Rome, Italy.
Parkinsons Dis. 2018 Aug 1;2018:7347859. doi: 10.1155/2018/7347859. eCollection 2018.
The Geriatric Depression Scale (GDS) is commonly used to assess depressive symptoms, but its psychometric properties have never been examined in Italian people with Parkinson's disease (PD). The aim of this study was to study the reliability and validity of the Italian version of the GDS in a sample of PD patients.
The GDS was administered to 74 patients with PD in order to study its internal consistency, test-retest reliability, construct, and discriminant validity.
The internal consistency of GDS was excellent ( = 0.903), as well as the test-retest reliability (ICC = 0.941 [95% CI: 0.886-0.970]). GDS showed a strong correlation with instruments related to the depression ( = 0.880) in PD ( = 0.712) and a weak correlation with generic measurement instruments (-0.320 < <-0.217). An area under the curve of 0.892 (95% CI 0.809-0.975) indicated a moderate capability to discriminate depressed patients to nondepressed patient, with a cutoff value between 15 and 16 points that predicts depression (sensitivity = 87%; specificity = 82%).
The GDS is a reliable and valid tool in a sample of Italian PD subjects; this scale can be used in clinical and research contexts.
老年抑郁量表（GDS）常用于评估抑郁症状，但其心理测量特性从未在意大利帕金森病（PD）患者中进行过研究。本研究的目的是在一组PD患者样本中研究意大利版GDS的信度和效度。
对74例PD患者进行GDS测试，以研究其内部一致性、重测信度、结构效度和区分效度。
GDS的内部一致性极佳（=0.903），重测信度也很高（ICC=0.941[95%CI：0.886-0.970]）。GDS与PD中与抑郁相关的量表呈强相关（=0.880），与一般测量量表呈弱相关（-0.320<<-0.217）。曲线下面积为0.892（95%CI 0.809-0.975），表明其区分抑郁患者和非抑郁患者的能力中等，截断值在15至16分之间，可预测抑郁（敏感性=87%；特异性=82%）。
GDS在意大利PD患者样本中是一种可靠且有效的工具；该量表可用于临床和研究环境。
