Cartwright Julyan H E, Piro Nicolas, Piro Oreste, Tuval Idan
Instituto Andaluz de Ciencias de la Tierra, CSIC-Universidad de Granada, Campus Fuentenueva, E-18071 Granada, Spain.
Birth Defects Res C Embryo Today. 2008 Jun;84(2):95-101. doi: 10.1002/bdrc.20127.
How does the clockwise motion of tens of monocilia drive a leftward flow in the node? And, as the observed flow is leftward, how is the fluid recirculating within the node, as it must, because the node is a closed structure? How does the nodal flow lead to left-right symmetry breaking in the embryo? These questions are within the realm of fluid physics, whose application to the problem of left-right symmetry breaking in vertebrates has led to important advances in the field.
数十根单纤毛的顺时针运动是如何在节点中驱动向左的流动的？而且，由于观察到的流动是向左的，那么在节点这个封闭结构中，流体又是如何如必然发生的那样进行再循环的呢？节点流动是如何导致胚胎左右对称性破缺的？这些问题属于流体物理学领域，该领域在脊椎动物左右对称性破缺问题上的应用已在该领域取得了重要进展。
