Puig N, Sayas M J, Montoro J A, Villalba J V, Pla A
Center of Transfusion of Comunidad Valenciana, Valencia, Spain.
Ann Hematol. 1991 Jun;62(6):232-4. doi: 10.1007/BF01729839.
We report a typical case of post-transfusion purpura (PTP) due to anti-PlA1 in a 65-year-old woman. Serological studies were carried out using flow cytometry (FCM). The patient also developed red cell alloantibodies that produced a delayed hemolytic transfusion reaction (DHTR) and broad HLA antibodies. Treatment with high-dose intravenous IgG (HDIgG; a first-generation preparation) was ineffective, but a course of steroids resulted in a rapid increase in the the platelet count.
我们报告了一例65岁女性因抗PlA1导致的典型输血后紫癜（PTP）病例。使用流式细胞术（FCM）进行了血清学研究。该患者还产生了红细胞同种抗体，引发了迟发性溶血性输血反应（DHTR）以及广泛的HLA抗体。高剂量静脉注射免疫球蛋白（HDIgG；第一代制剂）治疗无效，但使用类固醇治疗后血小板计数迅速上升。
