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输血导致抗P1A1被动转移继发的输血后紫癜。

Post-transfusion purpura secondary to passive transfer of anti-P1A1 by blood transfusion.

作者信息

Ballem P J, Buskard N A, Decary F, Doubroff P

出版信息

Br J Haematol. 1987 May;66(1):113-4. doi: 10.1111/j.1365-2141.1987.tb06899.x.

DOI:10.1111/j.1365-2141.1987.tb06899.x
PMID:3593646
Abstract

A patient developed severe post-transfusion purpura (PTP) following transfusion of two units of packed red blood cells. The timing of the patient's thrombocytopenia suggested passive immunization rather than the typical anamnestic response associated with classical PTP. Investigation of the blood donors revealed one with evidence of a platelet specific antibody of high titre. This donor was typed as P1A1 negative and the antibody was shown to have anti-P1A1 specificity.

摘要

一名患者在输注两单位浓缩红细胞后发生了严重的输血后紫癜(PTP)。患者血小板减少的时间提示为被动免疫,而非与经典PTP相关的典型回忆反应。对献血者的调查发现其中一人有高滴度血小板特异性抗体的证据。该献血者血型为P1A1阴性,且抗体显示具有抗P1A1特异性。

相似文献

1
Post-transfusion purpura secondary to passive transfer of anti-P1A1 by blood transfusion.输血导致抗P1A1被动转移继发的输血后紫癜。
Br J Haematol. 1987 May;66(1):113-4. doi: 10.1111/j.1365-2141.1987.tb06899.x.
2
Post-transfusion purpura associated with alloimmunization against the platelet-specific antigen, Baka.与针对血小板特异性抗原Baka的同种免疫相关的输血后紫癜
Am J Hematol. 1986 Jan;21(1):79-88. doi: 10.1002/ajh.2830210110.
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Post transfusion purpura and anti-Zwb (-P1A2).输血后紫癜与抗 Zwb(-P1A2)
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Post-transfusion purpura (PTP) due to anti-Zwb (-PlA2): the significance of IgG3 antibodies in PTP.由抗Zw(b)(-PlA2)引起的输血后紫癜(PTP):IgG3抗体在PTP中的意义
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Elution of anti-Zwa (-PIA1) from autologous platelets after normalization of platelet count in post-transfusion purpura.输血后紫癜患者血小板计数恢复正常后自体血小板上抗-Zwa(-PIA1)的洗脱
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[Posttransfusion thrombocytopenic purpura. 1st case described in Spain].[输血后血小板减少性紫癜。西班牙报道的首例病例]
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Posttransfusion thrombocytopenia.输血后血小板减少症
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Post-transfusion purpura associated with anti-Baka and anti-PIA2 platelet antibodies and delayed haemolytic transfusion reaction.与抗Baka和抗PIA2血小板抗体相关的输血后紫癜及迟发性溶血性输血反应。
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引用本文的文献

1
Anti-HPA-1b Mediated Posttransfusion Purpura: A Case Report.抗-HPA-1b介导的输血后紫癜:一例报告
Case Rep Med. 2013;2013:568364. doi: 10.1155/2013/568364. Epub 2014 Jan 16.
2
Severe thrombocytopenia in a child secondary to passive platelet antibody transfer from a plasma transfusion.一名儿童因输血导致被动血小板抗体转移继发严重血小板减少症。
J Pediatr Hematol Oncol. 2013 Jul;35(5):e226-8. doi: 10.1097/MPH.0b013e3182830c25.
3
Post-transfusion purpura as the main manifestation of a trilineal transfusion reaction, responsive to steroids: flow-cytometric investigation of granulocyte and platelet antibodies.
以三系输血反应为主要表现的输血后紫癜,对类固醇有反应:粒细胞和血小板抗体的流式细胞术研究
Ann Hematol. 1991 Jun;62(6):232-4. doi: 10.1007/BF01729839.