Minardi Giovanni, Manzara Carla, Pulignano Giovanni, Pino Paolo G, Pavaci Herribert, Sordi Martina, Musumeci Francesco
Department of Cardiology and Cardiovascular Surgery, Azienda Ospedaliera San Camillo-Forlanini, Rome, Italy.
J Med Case Rep. 2008 Jun 12;2:205. doi: 10.1186/1752-1947-2-205.
Mitral annular calcification is a common echocardiographic finding, especially in the elderly. Caseous calcification of the mitral annulus, however, is a relatively rare variant, having an echocardiographic prevalence of 0.6% in patients with mitral annular calcification. Caseous calcification needs to be differentiated from infected mitral annular calcification, mitral annular abscess and tumours. It is not malignant, and medical therapy with clinical follow-up is the therapeutic option. Surgery should be reserved for co-existent mitral valve dysfunction.
We report the case of a 69-year-old woman, in whom caseous calcification of the mitral annulus was found at transthoracic echocardiography. Cardiac surgery was performed because of significant mitral regurgitation and impairment of functional capacity.
Caseous calcification of the mitral annulus needs to be considered and confirmed by transthoracic echocardiography since there is potential for diagnostic confusion or misdiagnosis. This lesion appears to have a benign prognosis but, when associated with mitral valve dysfunction, cardiac surgery appears to be the best therapeutic option.
二尖瓣环钙化是一种常见的超声心动图表现,在老年人中尤为常见。然而,二尖瓣环干酪样钙化是一种相对罕见的变异类型,在二尖瓣环钙化患者中的超声心动图患病率为0.6%。干酪样钙化需要与感染性二尖瓣环钙化、二尖瓣环脓肿和肿瘤相鉴别。它并非恶性病变,临床随访的药物治疗是治疗选择。手术应仅用于并存的二尖瓣功能障碍。
我们报告一例69岁女性病例,经胸超声心动图检查发现二尖瓣环干酪样钙化。因严重二尖瓣反流和功能能力受损而进行了心脏手术。
由于存在诊断混淆或误诊的可能性,二尖瓣环干酪样钙化需要通过经胸超声心动图进行考虑和确诊。该病变似乎预后良好,但当与二尖瓣功能障碍相关时,心脏手术似乎是最佳治疗选择。