Shirshev S V
Biull Eksp Biol Med. 1991 Feb;111(2):181-3.
The functional activity of fractionated splenocytes were investigated in the syngeneic transfer system. Chorionic gonadotrophin (CG) was injected to ovariectomized and noncastrated lymphocyte donors, the T or B lymphocytes being isolated on a column with a nylon fiber and by means of anti-BaO-serum accordingly. In some series CG was introduced only into recipients before their being irradiated and before syngeneic cells transferring. CG has been stated to be capable of influencing either independently or by means of ovarian hormones splenic B lymphocytes without exhibiting a significant effect on T helper precursors as well as radioresistant cells of the splenic stroma. The character of immunoregulating effect was completely dependent on the presence of ovaries in mice and on the hormone dose.
在同基因转移系统中研究了分离的脾细胞的功能活性。向去卵巢和未去势的淋巴细胞供体注射绒毛膜促性腺激素（CG），然后分别通过尼龙纤维柱和抗BaO血清分离T淋巴细胞或B淋巴细胞。在一些实验系列中，仅在受体接受照射和同基因细胞转移之前向其引入CG。据称，CG能够独立地或通过卵巢激素影响脾脏B淋巴细胞，而对T辅助细胞前体以及脾脏基质的抗辐射细胞没有显著影响。免疫调节作用的性质完全取决于小鼠卵巢的存在和激素剂量。
