Papoutsakis E T, Meyer C L
Department of Chemical Engineering, Rice University, P.O. Box 1892, Houston, Texas 77251, USA.
Biotechnol Bioeng. 1985 Jan;27(1):50-66. doi: 10.1002/bit.260270108.
Using the available information of fermentation biochemistry, fermentation (stoichiometric) equations are derived for anaerobic saccharolytic fermentations of butanediol and mixed acids. The equations describe the interrelations among the fermentation products, biomass, and consumed substrate (glucose). The validity of the equations is tested using a variety of batch data from the literature. The validity of the equations is expected to extend to steady-state and transient fermentations, as well. Uses, improvements, and extensions of the equations are also discussed in detail. Among others, it is shown that the equations are useful for checking the consistency of experimental data, for calculating maximal yields and selectivities for the fermentation products, and calculating the extent of utilization of the Embden-Meyerhof-Parnas pathway versus the Hexose Monophosphate pathway of glucose utilization.
利用发酵生物化学的现有信息，推导了丁二醇和混合酸厌氧糖酵解发酵的发酵（化学计量）方程。这些方程描述了发酵产物、生物质和消耗的底物（葡萄糖）之间的相互关系。使用文献中的各种批次数据对这些方程的有效性进行了检验。预计这些方程的有效性也适用于稳态和瞬态发酵。还详细讨论了这些方程的用途、改进和扩展。其中表明，这些方程可用于检查实验数据的一致性，计算发酵产物的最大产率和选择性，以及计算葡萄糖利用的糖酵解途径与磷酸己糖途径的利用程度。
