Revell Liam J
Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts 02138, USA.
Am Nat. 2008 Jul;172(1):140-7. doi: 10.1086/588078.
Comparative biologists are sometimes interested in estimating the evolutionary rate along single branches in a phylogeny. I evaluate two methods by which the evolutionary rate along single branches can be compared with the evolutionary rate throughout the rest of the tree. The first is McPeek's contrasts method, and the second is a likelihood method presented independently in two recently published studies. Although the latter method was developed primarily for the comparison of rates among clades, the approach is equally suited for the analysis of evolutionary rate along single or isolated branches. I find that Type I error is acceptable in both methods but that power and parameter estimation are relatively poor in McPeek's method as it is typically applied.
比较生物学家有时会对估计系统发育中单个分支的进化速率感兴趣。我评估了两种方法，通过这两种方法可以将单个分支的进化速率与树的其余部分的进化速率进行比较。第一种是麦克皮克的对比法，第二种是在最近发表的两项研究中独立提出的似然法。尽管后一种方法主要是为比较类群间的速率而开发的，但该方法同样适用于分析单个或孤立分支的进化速率。我发现两种方法中的I型错误都是可以接受的，但麦克皮克方法在其通常应用中，功效和参数估计相对较差。
