Zhang Yun
Department of Organismic and Evolutionary Biology, Center for Brain Science, Harvard University, Cambridge MA 02138, United States.
Curr Opin Microbiol. 2008 Jun;11(3):257-61. doi: 10.1016/j.mib.2008.04.003. Epub 2008 Jun 12.
Individuals interact with environment through different neuronal functions, such as olfaction and mechanosensation; experience shapes these physiological functions. It is not well understood how an individual senses and processes multiple cues of natural stimuli in the environment and how experience modulates these physiological mechanisms. Recent molecular genetics and behavioral studies on the interactions of the genetic model organism Caenorhabditis elegans with pathogenic bacteria have provided insights on the molecular and cellular mechanisms underlying these regulatory processes.
个体通过不同的神经元功能与环境相互作用,如嗅觉和机械感觉;经验塑造这些生理功能。目前尚不清楚个体如何感知和处理环境中自然刺激的多种线索,以及经验如何调节这些生理机制。最近关于遗传模式生物秀丽隐杆线虫与致病细菌相互作用的分子遗传学和行为学研究,为这些调节过程背后的分子和细胞机制提供了见解。