Cohen Robyn T, Canino Glorisa J, Bird Hector R, Celedón Juan C
Channing Laboratory, Brigham and Women's Hospital , and Harvard Medical School, Boston, Massachusetts, USA.
Am J Respir Crit Care Med. 2008 Sep 1;178(5):453-9. doi: 10.1164/rccm.200711-1629OC. Epub 2008 Jun 12.
Puerto Ricans have the highest prevalence of and morbidity from asthma of all ethnic groups in the United States. One potential contributor to the high burden of asthma in Puerto Rican children is exposure to stress and violence.
To examine whether exposure to stress and violence is associated with an increased risk of asthma among Puerto Rican children.
This study was a population-based probability sample of children in the San Juan and Caguas metropolitan areas in Puerto Rico. Information was collected in a household survey of 1,213 children and their primary caretakers.
The prevalence of lifetime physician-diagnosed asthma was 39.6%. In the year before the survey, 14% of children had witnessed an act of violence, 7% had been victims of violence, and 6% had been victims of physical or sexual abuse. Although stressful life events and exposure to neighborhood violence were not associated with asthma, a history of physical or sexual abuse was associated with approximately twice the odds of current asthma (odd ratio [OR], 2.52; 95% confidence interval [CI], 1.27-5.00), health care use for asthma (OR, 1.95; 95% CI, 0.96-3.96), and medication use for asthma (OR, 2.35; 95% CI, 1.05-5.26).
Physical or sexual abuse is associated with high asthma morbidity among Puerto Rican children. To our knowledge, this is the first report of an association between childhood abuse and asthma. Our findings highlight the importance of screening for asthma among victims of childhood abuse, and to be aware of the possibility of physical or sexual abuse among children with asthma.
在美国所有种族群体中,波多黎各人哮喘的患病率和发病率最高。波多黎各儿童哮喘负担沉重的一个潜在因素是接触压力和暴力。
研究接触压力和暴力是否与波多黎各儿童哮喘风险增加有关。
本研究是以波多黎各圣胡安和卡瓜斯大都市区儿童为基础的概率样本。通过对1213名儿童及其主要照料者进行家庭调查收集信息。
终生经医生诊断为哮喘的患病率为39.6%。在调查前一年,14%的儿童目睹过暴力行为,7%的儿童曾是暴力受害者,6%的儿童曾遭受身体或性虐待。虽然生活应激事件和接触邻里暴力与哮喘无关,但有身体或性虐待史与当前患哮喘的几率增加约两倍相关(比值比[OR],2.52;95%置信区间[CI],1.27 - 5.00),因哮喘就医(OR,1.95;95%CI,0.96 - 3.96),以及使用哮喘药物(OR,2.35;95%CI,1.05 - 5.26)。
身体或性虐待与波多黎各儿童哮喘高发病率相关。据我们所知,这是关于儿童期虐待与哮喘之间关联的首份报告。我们的研究结果凸显了在儿童期虐待受害者中筛查哮喘的重要性,以及意识到哮喘儿童存在身体或性虐待的可能性。