Selim Heba, Shaheen Shagufta, Barakat Khaled, Selim Abdulhafez A
Department of Oral and Maxillofacial Surgery, Ain Shams University School of Dentistry, Cairo 11381, Egypt.
J Pediatr Surg. 2008 Jun;43(6):E25-9. doi: 10.1016/j.jpedsurg.2008.02.068.
Melanotic neuroectodermal tumor of infancy (MNTI) is an uncommon, fast-growing, pigmented neoplasm of neural crest origin. It primarily affects the maxilla of the infants during the first year of life. Approximately, a few hundred of these tumors have been reported in medical literature. We present a case of a newborn with MNTI involving the anterior maxillary region. The treatment included surgical excision of the lesion with safe margins, using an intraoral approach and removal of associated developing tooth buds. We made no attempt at immediate bone grafting. The patient had no recurrence at 1 year postoperatively. The diagnostic features and management alternatives of MNTI are discussed.
婴儿黑色素性神经外胚层肿瘤（MNTI）是一种罕见的、生长迅速的、起源于神经嵴的色素性肿瘤。它主要在婴儿出生后的第一年影响上颌骨。据医学文献报道，这类肿瘤大约有几百例。我们报告一例累及上颌前部区域的新生儿MNTI病例。治疗方法包括采用口内入路，在安全边界的情况下手术切除病变，并去除相关的发育中的牙胚。我们没有尝试立即进行骨移植。患者术后1年无复发。本文讨论了MNTI的诊断特征和治疗选择。
