Passàli Giulio C, Ralli Massimo, Galli Jacopo, Calò Lea, Paludetti Gaetano
ENT Department, Catholic University of the Sacred Heart Medical School, Rome, Italy.
Curr Opin Allergy Clin Immunol. 2008 Jun;8(3):238-42. doi: 10.1097/ACI.0b013e3282ffd6bb.
In the present review, the authors try to evaluate how relevant smell impairment is in patients suffering from allergic rhinitis and how it affects their quality of life. Smell dysfunction has a significant impact on the quality of life as it can lead to a wrong choice of food and intake, a reduction in appetite and eventually to weight loss, malnutrition, immunity reduction and worsening of medical illness. Patients with smell impairment are reported to use larger quantities of sugar and salt to highlight flavours, thus worsening their general health condition and increasing the risk of developing diabetes and hypertension.
Recent studies estimate that a complete loss of the sense of smell can be found in at least 1% of the US population, and that an impairment in the olfactory function can be highlighted in about 24% of individuals aged 53-97 years and 19% of individuals aged 20-92 years. Despite the high prevalence, subjective complaints do not accurately reflect the real disturbance experienced by the patient, and usually go unnoticed.
Current information in literature highlights the need for additional studies that concentrate on the impact of olfactory dysfunction on the quality of life of patients affected by allergic rhinitis.
在本综述中,作者试图评估嗅觉障碍在过敏性鼻炎患者中的相关性以及它如何影响患者的生活质量。嗅觉功能障碍对生活质量有重大影响,因为它可能导致食物选择和摄入量错误、食欲下降,最终导致体重减轻、营养不良、免疫力降低和病情恶化。据报道,嗅觉障碍患者会使用大量的糖和盐来突出味道,从而恶化他们的总体健康状况,并增加患糖尿病和高血压的风险。
最近的研究估计,在美国至少1%的人口中可发现完全丧失嗅觉,在53 - 97岁的个体中约24%以及20 - 92岁的个体中19%可发现嗅觉功能受损。尽管患病率很高,但主观症状并不能准确反映患者实际经历的干扰,通常会被忽视。
文献中的当前信息强调需要进行更多研究,专注于嗅觉功能障碍对过敏性鼻炎患者生活质量的影响。