氨基酸甲酯的简便合成方法。
A convenient synthesis of amino acid methyl esters.
作者信息
Li Jiabo, Sha Yaowu
机构信息
The Key Laboratory of Bioorganic Phosphorous Chemistry and Chemical Biology, Department of Chemistry, Tsinghua University, Beijing 100084, P. R. China.
出版信息
Molecules. 2008 May 8;13(5):1111-9. doi: 10.3390/molecules13051111.
Abstract
A series of amino acid methyl ester hydrochlorides were prepared in good to excellent yields by the room temperature reaction of amino acids with methanol in the presence of trimethylchlorosilane. This method is not only compatible with natural amino acids, but also with other aromatic and aliphatic amino acids.
摘要
通过氨基酸与甲醇在三甲基氯硅烷存在下于室温反应，以良好至优异的产率制备了一系列氨基酸甲酯盐酸盐。该方法不仅适用于天然氨基酸，也适用于其他芳香族和脂肪族氨基酸。
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