Bih Shin-Huey, Chien I-Chia, Chou Yiing-Jenq, Lin Ching-Heng, Lee Cheng-Hua, Chou Pesus
Department of Child and Adolescent Psychiatry, Bali Psychiatric Center, Taipei, Taiwan.
Soc Psychiatry Psychiatr Epidemiol. 2008 Nov;43(11):860-5. doi: 10.1007/s00127-008-0378-1. Epub 2008 Jun 13.
We used the NHI database to estimate the treated prevalence and incidence of bipolar disorder. The national health research institute (NHRI) provided a population based data file of 200,432 random subjects, about 1% of the population, for the study. We obtain a random sample of 136,045 subjects as a fixed cohort from 1996 to 2003. We identified study subjects who had at least one service claim during these years for either ambulatory or inpatient care with a principal diagnosis of bipolar disorder. The cumulative treated prevalence increased from 0.60 per 1,000 to 4.51 per 1,000 from 1996 to 2003. The annual treated incidence was around 0.48 per 1,000 per year to 0.71 per 1,000 per year during 1997-2003. Higher treated incidence was detected in the 45-64 (hazard ratio [HR], 1.63; 95% CI, 1.26-2.12) and 65 years or older age groups (HR, 1.57; 95% CI, 1.14-2.15), female (HR, 1.23; 95% CI, 1.04-1.46), non-aborigine (HR, 3.12; 95% CI, 1.26-7.75), with a fixed premium (HR, 1.60; 95% CI, 1.18-2.17), and those who lived in the eastern region (HR, 3.26; 95% CI, 2.31-4.59). According to the trends from 1996 to 2003, more persons with bipolar disorder had sought treatment in the NHI program in Taiwan. However, the treated prevalence of bipolar disorder in NHI was still lower than those of community studies in Western countries. In the future, we will continue to use NHI data to perform outcome evaluation and follow-up studies of bipolar disorder.
我们使用全民健康保险（NHI）数据库来估算双相情感障碍的治疗患病率和发病率。国家卫生研究院（NHRI）提供了一份基于人群的包含200,432名随机受试者的数据文件，约占总人口的1%，用于该研究。我们从1996年至2003年获得了136,045名受试者的随机样本作为固定队列。我们确定了在这些年份中至少有一次门诊或住院护理服务索赔且主要诊断为双相情感障碍的研究对象。从1996年到2003年，累积治疗患病率从每1000人0.60例增加到每1000人4.51例。1997 - 2003年期间，年治疗发病率约为每1000人每年0.48例至每1000人每年0.71例。在45 - 64岁（风险比[HR]，1.63；95%置信区间[CI]，1.26 - 2.12）和65岁及以上年龄组（HR，1.57；95% CI，1.14 - 2.15）、女性（HR，1.23；95% CI，1.04 - 1.46）、非原住民（HR，3.12；95% CI，1.26 - 7.75）、有固定保费者（HR，1.60；95% CI，1.18 - 2.17）以及居住在东部地区的人群（HR，3.26；95% CI，2.31 - 4.59）中检测到较高的治疗发病率。根据1996年至2003年的趋势，台湾有更多双相情感障碍患者在全民健康保险计划中寻求治疗。然而，全民健康保险中双相情感障碍的治疗患病率仍低于西方国家的社区研究结果。未来，我们将继续使用全民健康保险数据进行双相情感障碍治疗效果评估和随访研究。
