Chien I-Chia, Kuo Chien-Cheng, Bih Shin-Huey, Chou Yiing-Jenq, Lin Ching-Heng, Lee Cheng-Hua, Chou Pesus
Jianan Mental Hospital, Department of Health, Tainan, Taiwan.
Can J Psychiatry. 2007 Jan;52(1):28-36. doi: 10.1177/070674370705200106.
We used the National Health Insurance (NHI) database to examine the prevalence and incidence of treated major depressive disorder (MDD) and their associated factors.
The National Health Research Institute provided a database of 200 432 randomly selected subjects for study. We obtained a population-based random sample aged 15 years or older (n = 136 045) as a fixed cohort dated 1996 to 2003. We identified study subjects with a principal diagnosis of MDD who had at least one service claim during these years for either ambulatory or inpatient care.
From 1996 to 2003, the cumulative treated prevalence increased from 1.67 per 1000 to 17.24 per 1000. From 1997 to 2003, the annual treated incidence increased from 1.89 per 1000 to 2.58 per 1000. A higher incidence of treated MDD was detected in the groups aged 25 to 44 years (hazard ratio [HR] 1.28; 95% confidence interval [CI], 1.13 to 1.45), 45 to 64 years (HR 1.90; 95% CI, 1.66 to 2.16), and 65 years or older (HR 1.87; 95% CI, 1.59 to 2.20); in female subjects (HR 1.97; 95% CI, 1.80 to 2.15); in those with with an insurance amount of US $1281 or more (HR 1.15; 95% CI, 1.01 to 1.31); in those with a fixed premium (HR 1.44; 95% CI, 1.27 to 1.62); and among those who lived in urban areas (HR 1.22; 95% CI, 1.10 to 1.35).
For treated MDD, the prevalence and incidence in Taiwan were lower than in community studies in Western countries. Individuals with MDD are underdiagnosed and undertreated in Taiwan.
我们利用国民健康保险(NHI)数据库来研究已治疗的重度抑郁症(MDD)的患病率、发病率及其相关因素。
国立卫生研究院提供了一个包含200432名随机选取受试者的数据库用于研究。我们获取了一个以人群为基础的15岁及以上的随机样本(n = 136045)作为1996年至2003年的固定队列。我们确定了主要诊断为MDD且在这些年中至少有一次门诊或住院护理服务索赔的研究对象。
1996年至2003年,累积治疗患病率从每1000人1.67例增至每1000人17.24例。1997年至2003年,年治疗发病率从每1000人1.89例增至每1000人2.58例。在25至44岁组(风险比[HR] 1.28;95%置信区间[CI],1.13至1.45)、45至64岁组(HR 1.90;95% CI,1.66至2.16)以及65岁及以上组(HR 1.87;95% CI,1.59至2.20)中检测到较高的已治疗MDD发病率;在女性受试者中(HR 1.97;95% CI,1.80至2.15);在保险金额为1281美元或以上的人群中(HR 1.15;95% CI,1.01至1.31);在有固定保费的人群中(HR 1.44;95% CI,1.27至1.62);以及在居住在城市地区的人群中(HR 1.22;95% CI,1.10至1.35)。
对于已治疗的MDD,台湾地区的患病率和发病率低于西方国家的社区研究结果。台湾地区患有MDD的个体存在诊断不足和治疗不足的情况。