Mols Floortje, van den Hurk Corina J, Vingerhoets Ad J J M, Breed Wim P M
CoRPS-Center of Research on Psychology in Somatic Diseases, Tilburg University, Tilburg, the Netherlands.
Support Care Cancer. 2009 Feb;17(2):181-9. doi: 10.1007/s00520-008-0475-4. Epub 2008 Jun 17.
The objective of this prospective multicenter study was to obtain insight into the severity and burden of hair loss among cancer patients treated with chemotherapy. In addition, we described the effectiveness and burden of scalp cooling and the satisfaction with wigs, with hair regrowth, and with body image.
Breast cancer patients treated with (n = 98) and without (n = 168) scalp cooling completed questionnaires before chemotherapy and 3 weeks and 6 months after completion of chemotherapy.
Scalp cooling was effective in preventing chemotherapy-induced hair loss in 32 of 62 available patients (52%). Even though patients knew hair loss was temporary, it was a burden to 54% of them (n = 100). Scalp cooling was a burden for only 17 out of 51 patients (33%). Most patients who used a wig or head cover were satisfied with it (82%, n = 126). Patients were moderately satisfied with the regrowth of their hair after chemotherapy (mean 11.6; SD 2.53; range 0-20). Successfully cooled patients rated their hair as less important for their body image compared to patients who did experience hair loss (p = 0.014).
Chemotherapy-induced hair loss is perceived as burdensome. It may be prevented by offering scalp cooling which is often an effective method to prevent this form of hair loss and is tolerated well by patients. However, if possible, scalp-cooling techniques should be improved and their effectiveness should be increased because if scalp cooling is unsuccessful, patients' rate their hair loss as more burdensome compared to noncooled patients.
这项前瞻性多中心研究的目的是深入了解接受化疗的癌症患者脱发的严重程度和负担。此外，我们描述了头皮冷却的有效性和负担以及患者对假发、头发再生和身体形象的满意度。
98例接受头皮冷却和168例未接受头皮冷却的乳腺癌患者在化疗前、化疗结束后3周和6个月完成问卷调查。
在62例可用患者中，有32例（52%）通过头皮冷却有效预防了化疗引起的脱发。尽管患者知道脱发是暂时的，但仍有54%（n = 100）的患者感到这是一种负担。在51例患者中，只有17例（33%）觉得头皮冷却有负担。大多数使用假发或头套的患者对其感到满意（82%，n = 126）。患者对化疗后头发再生的满意度为中等（平均11.6；标准差2.53；范围0 - 20）。与经历脱发的患者相比，成功进行头皮冷却的患者认为头发对其身体形象的重要性较低（p = 0.014）。
化疗引起的脱发被认为是有负担的。提供头皮冷却可以预防脱发，这通常是预防这种脱发形式的有效方法，且患者耐受性良好。然而，如果可能的话，头皮冷却技术应该得到改进并提高其有效性，因为如果头皮冷却不成功，与未进行冷却的患者相比，患者会觉得脱发更难以承受。
