Perktold K, Resch M, Peter R O
Institute of Mathematics, Technical University Graz, Austria.
J Biomech. 1991;24(6):409-20. doi: 10.1016/0021-9290(91)90029-m.
To analyse the pulsatile flow field and the mechanical stresses in a three-dimensional carotid artery bifurcation model, computer simulation is applied. The approximation of the Navier-Stokes equations uses a pressure correction finite element method. Numerical results are presented for axial and secondary flow velocity and wall shear stresses with special emphasis on the fluid dynamics in the carotid sinus. This region is of major interest because it is affected preferentially by lesions. Detailed local flow studies as carried out here should lead to a further insight into the mechanisms of atherogenesis. The flow conditions used in the study were chosen according to Ku et al. (Arteriosclerosis 5, 293-302, 1985). The results of this numerical analysis agree in the essential features with their experimental results.
为了分析三维颈动脉分叉模型中的脉动流场和机械应力，采用了计算机模拟。纳维-斯托克斯方程的近似采用压力修正有限元法。给出了轴向和二次流速度以及壁面剪应力的数值结果，特别强调了颈动脉窦内的流体动力学。该区域备受关注，因为它更容易受到病变的影响。此处进行的详细局部血流研究应能进一步深入了解动脉粥样硬化的发病机制。研究中使用的流动条件是根据Ku等人（《动脉硬化》5，293 - 302，1985）的研究选择的。该数值分析的结果在基本特征上与他们的实验结果一致。
