Puri G D, Hegde H V, Jayant A, Bhukal I
Department of Anaesthesia and Intensive Care, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Anaesth Intensive Care. 2008 May;36(3):404-10. doi: 10.1177/0310057X0803600312.
The newly developed supralaryngeal airway Streamlined Liner of the Pharynx Airway (SLIPA) has been compared successfully to the LMA, but the haemodynamic response to its insertion has not been evaluated in a randomised study. We compared haemodynamic and Bispectral index (BIS) responses to insertion of the SLIPA with classic LMA after standardising the anaesthetic technique using BIS to monitor and control the anaesthetic depth. One hundred patients were randomised to receive either a classic LMA or SLIPA following induction with fentanyl and propofol titrated to a target BIS of 40 and compared heart rate, mean arterial pressure and BIS responses to insertion. There was a significant rise in mean arterial pressure from the pre-stimulus value (73.8 [10.6] mmHg, mean +/- SD) at two and three minutes (P<0.05) following insertion of the LMA with maximum rise (80.8 [11.5] mmHg) seen at two minutes. There was a significant rise in mean arterial pressure from the pre-stimulus value (73.2 [12.6] mmHg) at one, two, three, four and five minutes (P<0.05) following insertion of the SLIPA with maximum rise (86.9 [15.1] mmHg) observed at three minutes. Mean arterial pressure was significantly higher (P<0.05) with SLIPA at two, three, four and five minutes. BIS increased significantly (P<0.05) at one, two, three, four and five minutes following insertion of both the devices, but there was no significant difference between the groups. There was a significantly higher (P=0.001) incidence of blood on the device with the SLIPA (20/50 vs. 6/50 with LMA). Thus, insertion of SLIPA causes significantly higher blood-pressure response but similar BIS response compared to the LMA.
新研发的喉上气道——咽气道流线型衬垫(SLIPA)已成功与喉罩通气道(LMA)进行了比较,但尚未在随机研究中评估其插入时的血流动力学反应。我们使用脑电双频指数(BIS)监测和控制麻醉深度来标准化麻醉技术,比较了SLIPA与经典LMA插入时的血流动力学和BIS反应。100例患者在接受芬太尼和丙泊酚诱导后随机分为接受经典LMA或SLIPA组,将麻醉深度滴定至目标BIS值40,并比较插入时的心率、平均动脉压和BIS反应。插入LMA后两分钟和三分钟时,平均动脉压较刺激前值(73.8 [10.6] mmHg,平均值±标准差)显著升高(P<0.05),两分钟时升高幅度最大(80.8 [11.5] mmHg)。插入SLIPA后一分钟、两分钟、三分钟、四分钟和五分钟时,平均动脉压较刺激前值(73.2 [12.6] mmHg)显著升高(P<0.05),三分钟时升高幅度最大(86.9 [15.1] mmHg)。在两分钟、三分钟、四分钟和五分钟时,SLIPA组的平均动脉压显著更高(P<0.05)。插入两种装置后一分钟、两分钟、三分钟、四分钟和五分钟时,BIS均显著升高(P<0.05),但两组之间无显著差异。SLIPA装置上有血迹的发生率显著更高(P = 0.001)(20/50 vs. LMA为6/50)。因此,与LMA相比,插入SLIPA引起的血压反应显著更高,但BIS反应相似。